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Combinatorial Chemistry and Technology

Principles, Methods and Applications
Buch | Hardcover
448 Seiten
1999
Marcel Dekker Inc (Verlag)
978-0-8247-1960-9 (ISBN)
129,65 inkl. MwSt
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Provides coverage of combinatorial methodologies and technologies employed for the design, synthesis and screening of molecular "libraries". The text features assessments of computer-assisted approaches to guiding library synthesis.
"Provides comprehensive coverage of the current combinatorial methodologies and technologies employed for the design, synthesis, and screening of molecular ""libraries."" Features assessments of computer-assisted approaches to guiding library synthesis. Designed to satisfy the demand to create, produce in high yield and purity, and rapidly screen huge numbers of molecules."

Combinatorial chemistry and combinatorial technologies - principles and applications; synthesis and characterization of peptide libraries; solid-phase synthesis of organic libraries; resins, linkers, and reactions for solid-phase synthesis of organic libraries; solution-phase combinatorial libraries of small organic molecules; direct deconvolution techniques for pool libraries of small organic molecules; encoding techniques for pool libraries of small organic molecules; analytical characterization of synthetic organic libraries; automation in combinatorial chemistry; key ingredients for efficient high-throughput screening; computational aspects of combinatorial chemistry; biological libraries; peptide display libraries - design and construction; making and selecting from phage antibody libraries; biopanning; globular oligonucleotide screening via the SELEX process -aptamers as high-affinity, high-specificity compounds for drug development and proteomic diagnostics; economics of combinatorial chemistry and combinatorial technologies.

Erscheint lt. Verlag 1.7.1999
Verlagsort New York
Sprache englisch
Gewicht 771 g
Themenwelt Mathematik / Informatik Mathematik Graphentheorie
Naturwissenschaften Chemie Organische Chemie
ISBN-10 0-8247-1960-3 / 0824719603
ISBN-13 978-0-8247-1960-9 / 9780824719609
Zustand Neuware
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