Aquaporins (eBook)

Aquaporin Protein Structure and Selectivity Mechanisms.- Discovery of the Aquaporins and Development of the Field.- The AQP Structure and Functional Implications.- Dynamics and Energetics of Permeation Through Aquaporins. What Do We Learn from Molecular Dynamics Simulations?.- In Vitro Analysis and Modification of Aquaporin Pore Selectivity.- Aquaporin Function in Mammalian Water Homeostasis.- Aquaporins in the Kidney.- Regulation of Aquaporin-2 Trafficking.- Role of Aquaporin-4 in Cerebral Edema and Stroke.- Aquaporins as Potential Drug Targets for Meniere's Disease and its Related Diseases.- Aquaporins in Secretory Glands and their Role in Sjögren's Syndrome.- Aquaporin Glycerol Permeability in Mammalian Physiology.- Skin Aquaporins: Function in Hydration, Wound Healing, and Skin Epidermis Homeostasis.- Function of Aquaporin-7 in the Kidney and the Male Reproductive System.- Role of Aquaporin-7 and Aquaporin-9 in Glycerol Metabolism; Involvement in Obesity.- New Members of Mammalian Aquaporins: AQP10–AQP12.- Aquaporin Functions Apart from Water and Glycerol Transport.- Structural Function of MIP/Aquaporin 0 in the Eye Lens; Genetic Defects Lead to Congenital Inherited Cataracts.- pH Regulated Anion Permeability of Aquaporin-6.- Aquaglyceroporins and Metalloid Transport: Implications in Human Diseases.- Ammonia and Urea Permeability of Mammalian Aquaporins.- Knock-Out Models Reveal New Aquaporin Functions.- Towards Therapeutic Use of Aquaporins.- Design, Synthesis and Assaying of Potential Aquaporin Inhibitors.- Aquaporin-1 Gene Transfer to Correct Radiation-Induced Salivary Hypofunction.