Early Life Origins of Health and Disease (eBook)

Professor Owens is an internationally recognized researcher in developmental physiology and endocrinology and in the early life programming of adult health and disease, diabetes and obesity in particular. She has published over 140 research papers, reviews and book chapters. She has been invited to present numerous plenary lectures or symposia at international or national conferences, and to convene and chair international symposia and plenary sessions at the First, Second and Third World Congresses for the Developmental Origins of Adult Health and Disease (previously Fetal Origins of Adult Disease). She was awarded the McCance Medal for outstanding contributions to perinatal research.

The Developmental Origins of Health and Disease.- The Developmental Origins of Health and Disease.- Should we intervene to improve fetal growth?.- Developmental Origins of Cardiovascular Disease, Type 2 Diabetes and Obesity in Humans.- Growth and development of human twins.- Studies of Twins.- Practice-induced plasticity in the human motor cortex.- Prenatal Programming of Human Motor Function.- Adaptive Responses of Early Embryos to Their Microenvironment and Consequences for Post-Implantation Development.- Adaptive Responses of Early Embryos to Their Microenvironment and Consequences for Post-Implantation Development.- Modification of Epigenetic State through Dietary Manipulation in the Developing Mammalian Embryo.- Modification of Epigenetic State through Dietary Manipulation in the Developing Mammalian Embryo.- Overview of epigenetic mechanisms.- Critical Experiments to Determine if Early Nutritional Influences on Epigenetic Mechanisms Cause Metabolic Imprinting in Humans.- Nutritional programming and the development of hypertension.- Manipulation of the Maternal Diet in Rat Pregnancy.- Hypertension in pregnant women.- Programming Hypertension—Animal Models.- Developmental Programming of Cardiovascular Dysfunction.- Developmental Programming of Cardiovascular Dysfunction.- Kidney Development and Fetal Programming.- Kidney Development and Fetal Programming.- Programming of Obesity—Experimental Evidence.- Programming of Obesity—Experimental Evidence.- Placental delivery of amino acids. Utilization and production vs. transport.- Perinatal Programming of Adult Metabolic Homeostasis.- Programming Effects of Excess Glucocorticoid Exposure in Late Gestation.- Programming Effects of Excess Glucocorticoid Exposure in Late Gestation.- Emerging Frontiers.- Programming Effects of Moderate and Binge Alcohol Consumption.- Vitamin D in Pregnancy and Offspring Health.- The Fetal Origins of Adult Mental Illness.- Hypoxia, Fetal Growth and Developmental Origins of Health and Disease.