Handbook of Transfusion Medicine (eBook)

Front Cover 1
Handbook of Transfusion Medicine 4
Copyright Page 5
Contents 6
Contributors 10
Preface 12
Acknowledgments 14
List of Abbreviations 16
SECTION I: BLOOD COLLECTION, TESTING, AND PROCESSING 18
Chapter 1. Introduction to Blood Donors and Donation 20
Chapter 2. Infectious Disease Testing 28
Chapter 3. Component Preparation and Storage 36
SECTION II: BLOOD COMPONENTS 44
Chapter 4. Packed Red Blood Cells and Related Products 46
Chapter 5. Fresh Frozen Plasma and Related Products 56
Chapter 6. Cryoprecipitate and Related Products 64
Chapter 7. Platelets and Related Products 70
Chapter 8. Granulocytes 80
Chapter 9. Coagulation Factor Concentrates 86
Chapter 10. Albumin, Gamma Globulin, and Related Derivatives 96
SECTION III: RED BLOOD CELL ANTIGENS AND ANTIBODIES 106
Chapter 11. Red Blood Cell Antigens and Human Blood Groups 108
Chapter 12. Pretransfusion Compatibility Testing 124
Chapter 13. Special Investigations in the Workup of Unexpected Antibodies and Blood Group Incompatibilities 132
SECTION IV: SPECIALIZED COMPONENT PROCESSING OR TESTING 140
Chapter 14. Leukoreduced Products 142
Chapter 15. CMV and Other Virus-Safe Products 146
Chapter 16. Irradiated Components 154
Chapter 17. Washed and Volume-Reduced Components 160
SECTION V: HEMATOPOIETIC STEM CELLS AND RELATED CELLULAR PRODUCTS 164
Chapter 18. Bone-Marrow-Derived Hematopoietic Progenitor Cells 166
Chapter 19. Peripheral-Blood-Derived Hematopoietic Progenitor Cells 178
Chapter 20. Umbilical Cord Blood Stem Cells 188
Chapter 21. Mononuclear Cell Preparations 196
SECTION VI: SPECIALIZED TRANSFUSION SITUATIONS 204
Chapter 22. Approach to Acute Bleeding and Massive Transfusion 206
Chapter 23. Evaluation of the Bleeding Patient 214
Chapter 24. Approach to the Platelet Refractory Patient 226
Chapter 25. Approach to Transfusion in Obstetrics: Maternal and Fetal Considerations 238
Chapter 26. Transfusion Management of Infants and Children 248
Chapter 27. Approach to the Immunocompromised Patient 254
SECTION VII: TRANSFUSION REACTIONS 262
Chapter 28. Acute and Delayed Hemolytic Transfusion Reactions 264
Chapter 29. Febrile Nonhemolytic Transfusion Reactions 270
Chapter 30. Allergic Transfusion Reactions 276
Chapter 31. Other Noninfectious Complications of Transfusion 280
SECTION VIII: INFECTIOUS COMPLICATIONS OF TRANSFUSION 290
Chapter 32. Hepatitis 292
Chapter 33. CMV and Other Herpesviruses 302
Chapter 34. HIV and HTLV 310
Chapter 35. Other Transfusion-Transmitted Infections 318
Chapter 36. Bacterial Contamination of Blood Products 324
SECTION IX: THERAPEUTIC APHERESIS 330
Chapter 37. Overview and Practical Aspects of Therapeutic Apheresis 332
Chapter 38. Therapeutic Plasma Exchange: Rationales and Indications 340
Chapter 39. Therapeutic Cytapheresis: Red Blood Cell Exchange, Leukapheresis, and Thrombocytopheresis (Plateletpheresis) 350
SECTION X: CONSENT, QUALITY, AND RELATED ISSUES 360
Chapter 40. Informed Consent for Transfusion 362
Chapter 41. Home Transfusion 366
Chapter 42. Lookback and Recipient Notification, and Product Recalls and Withdrawls 372
Chapter 43. Process Improvement: One Essential of a Quality System 376
Subject Index 380