Key Features
* Provides a translational resource for scientists and clinicians working on prostate cancer
* Reviews current surgical interventions and highlights their related pitfalls
* Presents the latest laparoscopic techniques with figures and illustrations of step-by-step procedures
* Offers insight into the potential for novel approaches to treatment in the future
* Includes personal perspectives from patients
An important translational book bridging the gap between science and clinical medicine, Prostate Cancer reviews the biological processes that can be implicated in the disease, reviews current treatments, highlighting the pitfalls where relevant and examines the scientific developments that might result in novel treatments in the future.Key Features* Provides a translational resource for scientists and clinicians working on prostate cancer* Reviews current surgical interventions and highlights their related pitfalls* Presents the latest laparoscopic techniques with figures and illustrations of step-by-step procedures* Offers insight into the potential for novel approaches to treatment in the future* Includes personal perspectives from patients
Front Cover 1
Prostate Cancer 4
Copyright Page 5
Contents 6
Foreword 10
Preface 12
List of contributors 14
Part I: Etiology, Pathology and Tumor Biology 24
Chapter 1. Population Screening for Prostate Cancer and Early Detection in High-risk African American Men, 26
Chapter 2. Molecular Mechanism of Prostate Cancer Invasion and Metastasis, 34
Chapter 3. Does Prostate Cancer Represent More than One Cancer? 52
Chapter 4. High-grade Prostatic Intraepithelial Neoplasia 58
Chapter 5. Update on the Regulation of Apoptosis in Prostate Cancer 68
Chapter 6. Prostate Cancer with Other Primary Malignancies 78
Chapter 7. Angiogenesis, Growth Factors, Microvessel Density, p53 and p21 in Prostate Cancer 86
Chapter 8. Staging of Prostate Cancer, PSA Issues Leading up to Prostate Biopsy and Biopsy Technique 92
Chapter 9. Prostate Biopsy: Who, How and When? 100
Part II: Genetic Susceptibility and Hereditary Predisposition, Screening and Counseling 110
Chapter 10. Prostate Cancer Prevention: Strategies and Realities 112
Chapter 11. Genetic Changes and Their Prognostic Significance in Prostate Cancer 124
Part III: Epidemiology 136
Chapter 12. Cancer of the Prostate: Incidence in the USA 138
Chapter 13. Race, Ethnicity, Religion, Marital Status and Prostate Cancer in the USA 144
Chapter 14. Prostate Cancer: Detection and Biopsy Strategies 152
Chapter 15. Prostate Cancer Treatment Outcomes between African Americans and Caucasians 160
Chapter 16. Hereditary Prostate Cancer 168
Chapter 17. Breast and Prostate Cancer: a Comparison of Two Common Endocrinologic Malignancies, 182
Chapter 18. Artificial Neural Networks for Predictive Modeling in Prostate Cancer 190
Part IV: Prevention of Prostate Cancer 196
Chapter 19. Obesity, Aging and Immunity in Prostate Cancer 198
Chapter 20. Prevention of Prostate Cancer: The Role of Diet 208
Chapter 21. What are the Effects of Dietary Supplements (Selenium and Vitamin E) or Aspirin/NSAIDs on Prostate Cancer? 216
Chapter 22. Effects of Smoking, Alcohol, Exercise and Sun Exposure on Prostate Cancer 230
Chapter 23. Prostate Cancer on the Internet: Review 2002 240
Part V: Treatment 252
Chapter 24. The Decision-making Process for Prostate Cancer 254
Chapter 25. Expectant Management in 2002: Rationale and Indications 276
Part VI: Surgery 282
Chapter 26. Is Surgery still Necessary for Prostate Cancer? 284
Chapter 27. Indications for Pelvic Lymphadenectomy 290
Chapter 28. The Surgical Anatomy of the Prostate 296
Chapter 29. Radical Retropubic Prostatectomy 302
Chapter 30. Sural Nerve Interposition Graft During Radical Prostatectomy 312
Chapter 31. Radical Prostatectomy: the Retropubic Antegrade Approach 324
Chapter 32. Mini-lap Radical Retropubic Prostatectomy 334
Chapter 33. Radical Perineal Prostatectomy 342
Chapter 34. Stress Incontinence After Radical Prostatectomy 350
Chapter 35. Prognostic Significance of Positive Surgical Margins 362
Chapter 36. Bloodless Surgery and Radical Retropubic Prostatectomy 370
Chapter 37. Laparoscopic Radical Prostatectomy 378
Chapter 38. Pitfalls of Laparoscopic Radical Prostatectomy 386
Chapter 39. Robotic Retropubic Radical Prostatectomy 394
Part VII: Radiation Therapy 398
Chapter 40. Does Radiation Therapy Really Work for Prostate Cancer? 400
Chapter 41. Is One Form of Radiation Therapy Better Over Another? 410
Chapter 42. Radiation Therapy for Early-stage Prostate Cancer Could It Parallel Prostatectomy? 414
Chapter 43. Brachytherapy for Prostate Cancer 426
Chapter Part. VIII: Hormonal Therapy/Chemotherapy 432
Chapter 44. Osteoporosis and Prostate Cancer 434
Chapter 45. Neoadjuvant Hormonal Treatment Prior to Curative Treatment in Prostate Cancer 438
Chapter 46. Androgen-independent Prostate Cancer: The Evolving Role of Chemotherapy 446
Chapter 47. Monotherapy with Antiandrogens in the Treatment of Prostate Cancer 458
Part IX: Cryoablation 464
Chapter 48. Is Cyroablation Here to Stay? 466
Chapter 49. Salvage Cryoablation of the Prostate 474
Part X: Patient’s Experiences 482
Chapter 50. Quality of Life: Impact of Prostate Cancer and its Treatment 484
Chapter 51. Sexual Aspects of Prostate Cancer Treatment 494
Chapter 52. Prostate Cancer: A Patient’s Perspective 504
Part XI: Governmental Policies 508
Chapter 53. Prostate Cancer Economics 510
Part XII: New Horizons for Prostate Cancer 516
Chapter 54. Molecular Therapeutics in Prostate Cancer 518
Chapter 55. Antioxidants and Phytotherapy 540
Chapter 56. What is the Newest Technology in Treating Prostate Cancer? Transrectal High-intensity Focused Ultrasound 552
Chapter 57. New Markers for Prostate Cancer Detection: What is on the Horizon? 558
Chapter 58. Are Vaccinations for Prostate Cancer Realistic? 568
Index 578
Color Plate Section 594
Contributors
Clément-Claude Abbou
Service d’Urologie CHU Henri Mondor, 51 Avenue Du M1. De Lattre de Tassigny, 94010 Créteil-cedex, France
Neil A. Abrahams
Department of Anatomic Pathology, 9500 Euclid Avenue, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Bulent Akduman
Department of Urology, University of Colorado Health Science Center, Campus Box F710, 4200 E. Ninth Avenue, Denver, CO 80262, USA
Thomas Anderson, Jr.
Office of Community Relations, University Services Building, Suite 302, Temple University, 1601 N. Broad Street, Philadelphia, PA 19122, USA
Gerald L. Andriole
Division of Urologic Surgery, Washington University School of Medicine, 4960 Children’s Place, Box 8242, St Louis, MO 63110-1002, USA
Ronald E. Anglade
Department of Urology, Boston University School of Medicine, 720 Harrison Avenue, Suite 606, Boston, MA 02118, USA
Seetharaman Ashok
Department of Urology, Rhode Island Hospital, Brown Medical School, 2 Dudley Street, Suite 174, Providence, RI 02905, USA
R. Joseph Babaian, rbabaian@mail.mdanderson.org
Department of Urology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd. Box 446, Houston, TX 77030, USA
Richard K. Babayan
Department of Urology, Boston University School of Medicine, 720 Harrison Avenue, Suite 606, Boston, MA 02118, USA
David G. Bostwick, bostwick@bostwicklaboratories.com
Bostwick Laboratories, 2807 N. Parham Road, Richmond, VA 23294, USA
Simon R.J. Bott
Institute of Urology and Nephrology, University College London, Royal Free and University College, Medical School, 3rd Floor, Charles Bell House, 67 Riding House Street, London W1W 7EY, UK
Steven C. Campbell, scampb6@lumc.edu
Department of Urology and The Cardinal Bernardin, Cancer Center, Loyola University Medical School, 2160 S. 1st Avenue, Building 54, Room 237, Maywood, IL 60153, USA
Eduardo Canto
Scott Department of Urology, Baylor College of Medicine, Texas Medical Center, 6560 Fannin, Suite 2100, Houston, TX 77030, USA
David Crawford
Department of Urology, University of Colorado Health Science Center, Campus Box F710, 4200 E. Ninth Avenue, Denver, CO 80262, USA
Paul Crispen
Department of Urology, Temple University Hospital, Suite 350, Parkinson Pavilion, 3401 N. Broad Street, Philadelphia, PA 19140, USA
Philipp Dahm
Duke University Medical Center, Division of Urology, Department of Surgery, Box 2977, Durham, NC 27710, USA
John W. Davis
Department of Urology and The Virginia Prostate, Center of the Eastern Virginia Medical School, and Sentara Cancer Institute, Yoo West Bramblelon Avenue, Suite 100, Norfolk, VA 23501, USA
Frans M.J. Debruyne
Department of Urology – 426, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Steven J. DiBiase
Department of Radiation Oncology, University of Maryland School of Medicine, 22 S. Greene Street, Baltimore, MD 21201, USA
Bob Djavan
Department of Urology, University of Vienna, Wahringer Gurtel 18-20, 1090 Vienna, Austria
Ehab El-Gabry
Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA
Lars Ellison
Johns Hopkins Hospital, 600 North Wolfe Street, Carnegie 298, Baltimore, MD 21287,USA
Paul F. Engstrom
Department of Population Sciences, Fox Chase Cancer Center, Temple University School of Medicine, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
Abelardo Errejon
Department of Urology, University of Colorado Health Science Center, Campus Box F710, 4200 E. Ninth Avenue, Denver, CO 80262, USA
John M. Fitzpatrick
Department of Surgery, Mater Misericordiae Hospital, Conway Institute, University College Dublin, 47 Eccles Street, Dublin 7, Ireland
Neil Fleshner
Division of Urology, Princess Margaret Hospital, 610 University Avenue, Room 3-130, Toronto, Ontario M5G 2M9, Canada
Eduard J. Gamito
Department of Urology, University of Colorado Health Science Center, Campus Box F710, 4200 E. Ninth Avenue, Denver, CO 80262, USA
Ellen Gaynor
Department of Medicine, Loyola University Medical School and, The Cardinal Bernadin Cancer Center, 2160 S. 1st Avenue, Building 54, Room 237, Maywood, IL 60153, USA
Glen Gejerman
Department of Radiation Oncology, Hackensack University Medical Center, 30 Prospect Avenue, Hackensack, NJ 07601, USA
Inderbir S. Gill
Section of Laparoscopic and Minimally Invasive Surgery, Department of Urology, A-100, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Phillip C. Ginsberg
Department of Surgery, Division of Urology, Albert Einstein Medical Center, 5401 Old York Road, Suite 500, Philadelphia, PA 19141, USA
Ciril J. Godec
Department of Urology, Long Island College Hospital, 339 Hicks Street, Brooklyn, New York, NY 11201, USA
Kazuo Gohji
Department of Urology, Osaka Medical College, 2-7 Daigakumatchi, Takatsuki, 569-8686, Japan
Leonard G. Gomella
Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA
Richard Greenberg
Department of Urologic Oncology, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
Richard C. Harkaway
Department of Surgery, Division of Urology, Albert Einstein Medical Center, 5401 Old York Road, Suite 500, Philadelphia, PA 19141, USA
Beth A. Hellerstedt
University of Michigan, 7303 CCGC, Box 0946, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Eric M. Horwitz
Department of Radiation Oncology, Fox Chase Cancer Center, Temple University School of Medicine, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
András Hoznek
Service d’Urologie CHU Henri Mondor, 51 Avenue Du M1. De Lattre de Tassigny, 94010 Créteil-cedex, France
William B. Isaacs
Brady Urological Institute, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA
Jonathan Izawa
Department of Surgery and Oncology, Division of Urology, The University of Western Ontario, London Health Sciences Center, South Street, Victoria Campus, London, Ontario NGA 4G5, Canada
Stephen C. Jacobs, sjacobs@smail.umaryland.edu
Department of Surgery, University of Maryland School of Medicine, 22 S. Greene Street, Baltimore, MD 21201, USA
Matthew Karlovsky
Department of Urology, Temple University Hospital, Suite 350, Parkinson Pavilion, 3401 N. Broad Street, Philadelphia, PA 19140, USA
Michael Kattan, kattanm@mskcc.org
Department of Urology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Aaron E. Katz
Department of Urology, College of Physicians and Surgeons, Columbia University, Atchley Pavilion 11th Floor, 161 Fort Washington Avenue, New York, NY 10032, USA
Roger S. Kirby
Department of Urology, St George’s Hospital, Blackshaw Road, London SW17 OQT, UK
Sohei Kitazawa
Department of Molecular Pathology, Kobe University Graduate School of Medicine, 7-5-1 Kusonoki-cho, Chuo-ku, Kobe, 650-0017, Japan
Laurence Klotz
Division of Urology, Sunnybrook and Women’s College Health Sciences Centre, University of Toronto, 2075 Bayview Avenue # MG 408, Toronto, Ontario M4N 3M5, Canada
Vladimir Kolenko
Department of Surgical/Urologic Oncology, Fox Chase Cancer Center, Temple University School of Medicine, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
Andre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Temple University School of Medicine, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
Richard E. Link
Scott Department of Urology, Baylor College of Medicine, Texas Medical Center, 6560 Fannin, Suite 2100, Houston, TX 77030, USA
Stephan Madersbacher
Department of Urology, University of Vienna, Warhinger Gurtel 18–20, 1090, Austria
S. Bruce Malkowicz, Malkowic@mail.med.upenn.edu
Division of Urology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
Michael Marberger
Department of Urology, University of Vienna, Wahringer Gurtel 18-20, 1090 Vienna, Austria
Fray Marshall
Department of Urology, Emory University School of Medicine, Building A, Rm 3225, Atlanta, GA 30322,...
| Erscheint lt. Verlag | 11.7.2003 |
|---|---|
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Urologie | |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| ISBN-10 | 0-08-049789-6 / 0080497896 |
| ISBN-13 | 978-0-08-049789-1 / 9780080497891 |
| Haben Sie eine Frage zum Produkt? |
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