Fenner's Veterinary Virology (eBook)

Front Cover 1
Fenner’s Veterinary Virology 4
Copyright Page 5
Contents 8
Contributors 20
Acknowledgments 22
Part I: The Principles of Veterinary and Zoonotic Virology 24
Chapter 1. The Nature of Viruses 26
Introduction: A Brief History of Animal Virology 26
Characteristics of Viruses 29
Viral Morphology 33
Viral Taxonomy 37
Chapter 2. Virus Replication 44
Growth of viruses 44
Virus Replication 47
Quantitative Assays of Viruses 62
Special Case of Defective Interfering Mutants 64
Chapter 3. Pathogenesis of Viral Infections and Diseases 66
Interplay of Viral Virulence and Host Resistance, or Susceptibility Factors in Expression of Viral Diseases 66
Mechanisms of Viral Infection and Virus Dissemination 69
Mechanisms of Viral Injury and Disease 77
Virus-Induced Neoplasia 90
Chapter 4. Antiviral Immunity and Prophylaxis 98
Host Immunity to Viral Infections 98
Viral Mechanisms of Avoidance and Escape 109
Vaccines and Vaccination Against Viral Diseases 110
Other Strategies for Antiviral Prophylaxis and Treatment 121
Viruses as Vectors for Gene Therapy 122
Chapter 5. Laboratory Diagnosis of Viral Infections 124
Rationale for Specific Diagnosis 125
Collection, Packaging, and Transport of Specimens 128
Diagnosis of Viral Infections by Gross Evaluation and Histopathology 130
Methods of Detection of Viruses 130
Nucleic Acid (Viral Genomic) Sequencing 139
Detection and Quantitation of Virus-Specific Antibodies (Serologic Diagnosis) 140
Interpretation of Laboratory Findings 144
Chapter 6. Epidemiology and Control of Viral Diseases 148
Epidemiology of Viral Infections 148
Emerging Viral Diseases 159
Surveillance, Prevention, Control, and Eradication of Viral Diseases 165
Part II: Veterinary and Zoonotic Viruses 172
Chapter 7. Poxviridae 174
Properties of Poxviruses 175
Members of the Genus Orthopoxvirus 178
Members of the Genus Capripoxvirus 180
Members of the Genus Suipoxvirus 183
Members of the Genus Leporipoxvirus 183
Members of the Genus Molluscipoxvirus 184
Members of the Genus Yatapoxvirus 184
Members of the Genus Avipoxvirus 185
Members of the Genus Parapoxvirus 186
Poxviruses of Fish 187
Other Poxviruses 188
Chapter 8. Asfarviridae and Iridoviridae 190
Members of the Family Asfarviridae 190
Members of the Family Iridoviridae 195
Chapter 9. Herpesvirales 202
Properties of Herpesviruses 203
Members of the Family Herpesviridae, Subfamily Alphaherpesvirinae 207
Members of the Family Herpesviridae, Subfamily Betaherpesvirinae 218
Members of the Family Herpesviridae, Subfamily Gammaherpesvirinae 219
Unassigned Members of the Family Herpesviridae 221
Members of Families Alloherpesviridae and Malacoherpesviridae 222
Chapter 10. Adenoviridae 226
Properties of Adenoviruses 226
Members of the Genus Mastadenovirus 230
Members of the Genus Aviadenovirus 233
Members of the Genus Atadenovirus 233
Members of the Genus Siadenovirus 235
Other Adenoviruses 235
Chapter 11. Papillomaviridae and Polyomaviridae 236
Members of the Family Papillomaviridae 236
Members of the Family Polyomaviridae 244
Chapter 12. Parvoviridae 248
Properties of Parvoviruses 248
Members of the Genus Parvovirus 251
Members of the Genus Erythrovirus 257
Members of the Genus Amdovirus 257
Members of the Genus Dependovirus 258
Members of the Genus Bocavirus 258
Other Parvoviruses 258
Chapter 13. Circoviridae 260
Properties of Circoviruses 260
Beak and Feather Disease Virus 262
Other Avian Circoviruses 263
Porcine Circoviruses 263
Chicken Anemia Virus 265
Chapter 14. Retroviridae 266
Properties of Retroviruses 267
Members of the Subfamily Orthoretrovirinae, Genus Alpharetrovirus 274
Members of the Subfamily Orthoretrovirinae, Genus Betaretrovirus 279
Members of the Subfamily Orthoretrovirinae, Genus Gammaretrovirus 282
Members of the Subfamily Orthoretrovirinae, Genus Deltaretrovirus 287
Members of the Subfamily Orthoretrovirinae, Genus Epsilonretrovirus 289
Members of the Subfamily Orthoretrovirinae, Genus Lentivirus 289
Members of the Subfamily Spumaretrovirinae 296
Miscellaneous Retrovirus-Associated Diseases 297
Chapter 15. Reoviridae 298
Properties of Reoviruses 299
Members of the Genus Orthoreovirus 304
Members of the Genus Orbivirus 306
Members of the Genus Rotavirus 311
Members of the Genus Coltivirus 313
Members of the Genus Aquareovirus 313
Other Reoviruses 314
Chapter 16. Birnaviridae 316
Properties of Birnaviruses 316
Infectious Bursal Disease Virus 318
Infectious Pancreatic Necrosis Virus 320
Chapter 17. Paramyxoviridae 322
Properties of Paramyxoviruses 324
Members of the Subfamily Paramyxovirinae, Genus Respirovirus 331
Members of the Subfamily Paramyxovirinae, Genus Rubulavirus 333
Members of the Subfamily Paramyxovirinae, Genus avulavirus 334
Members of the Subfamily Paramyxovirinae, Genus Morbillivirus 337
Members of the Subfamily Paramyxovirinae, Genus Henipavirus 344
Members of the Subfamily Pneumovirinae, Genus Pneumovirus 346
Members of the Subfamily Pneumovirinae, Genus Metapneumovirus 347
Unclassified Members of Family Paramyxoviridae 348
Chapter 18. Rhabdoviridae 350
Properties of Rhabdoviruses 350
Members of the Genus Lyssavirus 354
Members of the Genus Vesiculovirus 359
Members of the Genus Ephemerovirus 361
Rhabdoviruses Diseases of Fish: Genera Vesiculovirus and Novirhabdovirus 362
Chapter 19. Filoviridae 366
Properties of Filoviruses 366
Marburg and Ebola Hemorrhagic Fever Viruses 368
Chapter 20. Bornaviridae 372
Properties of Borna Disease Virus 372
Borna Disease Virus 373
Avian Bornavirus 375
Chapter 21. Orthomyxoviridae 376
Properties of Orthomyxoviruses 379
Members of the Genus Influenzavirus A 384
Members of the Genus Isavirus 392
Other Orthomyxoviruses 393
Chapter 22. Bunyaviridae 394
Properties of Bunyaviruses 395
Members of the Genus Orthobunyavirus 398
Members of the Genus Phlebovirus 399
Members of the Genus Nairovirus 403
Members of the Genus Hantavirus 404
Chapter 23. Arenaviridae 408
Properties of Arenaviruses 408
Old World Arenaviruses 411
New World Arenaviruses 414
Chapter 24. Coronaviridae 416
Properties of Coronaviruses 417
Members of the Genus Coronavirus 422
Members of the Genus Torovirus 435
Chapter 25. Arteriviridae and Roniviridae 438
Properties of Arteriviruses and Roniviruses 438
Members of the Family Arteriviridae, Genus Arterivirus 441
Members of the Family RonivirIdae, Genus Okavirus 446
Unclassified Nidoviruses of Fish 446
Chapter 26. Picornaviridae 448
Properties of Picornaviruses 449
Members of the Genus Aphthovirus 454
Members of the Genus Enterovirus 458
Members of the Genus Teschovirus 460
Members of the Genus Cardiovirus 461
Members of the Genus Erbovirus 462
Members of the Genus Kobuvirus 462
Unclassified Picornaviruses 462
Chapter 27. Caliciviridae 466
Properties of Caliciviruses 466
Members of the Genus Vesivirus 469
Members of the Genus Lagovirus 472
Members of the Genus Norovirus 473
Other Calicivirus infections of Animals 473
Chapter 28. Astroviridae 474
Properties of Astroviruses 474
Turkey Astrovirus 476
Avian Nephritis Virus 477
Other Astroviruses 477
Chapter 29. Togaviridae 478
Properties of Togaviruses 479
Members of the Genus Alphavirus Equine Alphaviruses 481
Other Zoonotic AlphaViruses 486
Salmonid Alphaviruses 486
Chapter 30. Flaviviridae 490
Properties of Flaviviruses 492
Members of the Genus Flavivirus: Mosquito-Borne Flaviviruses 494
Members of the Genus Flavivirus: Tick-Borne Encephalitis Viruses 498
Members of the Genus Pestivirus 498
Chapter 31. Other Viruses: Hepeviruses, Hepadnaviridae, Deltaviruses, Anelloviruses, and Unclassified Viruses 506
Members of the Genus Hepevirus 506
Members of the Family Hepadnaviridae 508
Members of the Floating Genus Deltavirus 509
Members of the Floating Genus Anellovirus 510
Unclassified Arboviruses 510
Chapter 32. Prions: Agents of Transmissible Spongiform Encephalopathies 512
Properties of Prions 513
Scrapie 515
Sporadic Spongiform Encephalopathy of Sheep and Goats 517
Bovine Spongiform Encephalopathy 517
Atypical Bovine Spongiform Encephalopathy 519
Transmissible Mink Encephalopathy 519
Chronic Wasting Disease of Deer and Elk 519
Human Prion Diseases 519
Index 522
A 522
B 522
C 523
D 524
E 524
F 525
G 525
H 526
I 526
J 526
K 527
L 527
M 527
N 527
O 527
P 527
Q 528
R 528
S 529
T 530
U 530
V 530
W 530
X 530
Y 530