Endocrine-Disrupting Chemicals (eBook)

From Basic Research to Clinical Practice

Andrea C. Gore (Herausgeber)

eBook Download: PDF
2007 | 2007
XII, 361 Seiten
Humana Press (Verlag)
978-1-59745-107-9 (ISBN)

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This book provides comprehensive coverage of the three most important themes in the field of Endocrine Disrupting Chemicals (EDC) research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs.


Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians' office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.

Contents 7
Acknowledgments 9
Contributors 11
The Basic Biology of Endocrine Disruption 13
Introduction to Endocrine-Disrupting Chemicals 14
Endocrine Disruption and the Female 20
Endocrine Disruption in the Male 43
Endocrine-Disrupting Chemicals and the Brain 73
Heavy Metals as Endocrine- Disrupting Chemicals 120
Cellular Mechanisms of Endocrine Disruption 143
Endocrine Disruptors, Epigenetically Induced Changes, and Transgenerational Transmission of Characters and Epigenetic States 183
The Biology of EDCs in Humans 198
Implications of Thyroid Hormone Signaling Through the Phosphoinositide- 3 Kinase for Xenobiotic Disruption of Human Health 199
Endocrine Disruption and Reproductive Outcomes in Women 209
Epidemiologic Evidence on the Relationship Between Environmental Endocrine Disruptors and Male Reproductive and Developmental Health 230
Human Exposures and Body Burdens of Endocrine- Disrupting Chemicals 257
Implications and Mitigations of EDCs 273
Policy Implications of Endocrine- Disrupting Chemicals in Humans 274
Talking With Patients and the Public About Endocrine- Disrupting Chemicals 291
Community Interventions to Reduce Exposure to Chemicals with Endocrine- Disrupting Properties 310
What Can We Do About Endocrine- Disrupting Chemicals? 330
Index 349

Erscheint lt. Verlag 8.6.2007
Reihe/Serie Contemporary Endocrinology
Contemporary Endocrinology
Zusatzinfo XII, 361 p. 36 illus.
Verlagsort Totowa
Sprache englisch
Themenwelt Medizinische Fachgebiete Innere Medizin Endokrinologie
Medizin / Pharmazie Pflege
Naturwissenschaften Chemie
Technik
Schlagworte Diabetes • Hormone • hormone signaling • thyroid hormone • transgen • Translation
ISBN-10 1-59745-107-X / 159745107X
ISBN-13 978-1-59745-107-9 / 9781597451079
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