Radiation Oncology: A Physicist's-Eye View (eBook)

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2007 | 2008
XII, 330 Seiten
Springer New York (Verlag)
978-0-387-72645-8 (ISBN)

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Radiation Oncology: A Physicist's-Eye View - Michael Goitein
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The papers collected in this hugely useful volume cover the principle physical and biological aspects of radiation therapy and in addition, address practical clinical considerations in the planning and delivering of that therapy. The importance of the assessment of uncertainties is emphasized. Topics include an overview of the physics of the interactions of radiation with matter and the definition of the goals and the design of radiation therapy approaches.



Michael Goitein, Ph.D., is Professor of Radiation Therapy Emeritus (Radiation Biophysics) Harvard Medical School.  He is certified in Therapeutic Radiological Physics by the American Board of Radiology and in Medical Physics by the Swiss Society of Medical Physics and Biology. He is also a Fellow in the American Association of Physicists in Medicine and an Honorary Member of the Belgian Society of Radiotherapy and Oncology.


Radiation Oncology: A Physicist's-Eye View was written for both physicists and medical oncologists with the aim of helping them approach the use of radiation in the treatment of cancer with understanding, confidence, and imagination.  The book will let practitioners in one field understand the problems of, and find solutions for, practitioners in the other. It will help them to know "e;why"e; certain approaches are fruitful while, at the same time, encouraging them to ask the question "e;Why not?"e; in the face of assertions that some proposal of theirs is impractical, unreasonable, or impossible. Unlike a textbook, formal and complete developments of the topics are not among the goals. Instead, the reader will develop a foundation for understanding what the author has found to be matters of importance in radiation oncology during over thirty years of experience. Presentations cover, in largely non-technical language, the principal physical and biological aspects of radiation treatment and address practical clinical considerations in planning and delivering therapy. The importance of the assessment of uncertainties is emphasized. Topics include: an overview of the physics of the interactions of radiation with matter; the definition of the goals and the design of radiation therapy approaches; living with uncertainty; biophysical models of radiation damage; computer-based optimization of treatments; and proton therapy. Formulae and quantitation in general have been avoided in the belief that an understanding of the majority of important medical and biological issues in radiation oncology generally cannot be achieved through mathematical relationships.  This unique and highly readable book will be indispensable both to beginners and to those with experience in either medical physics or radiation oncology.The author, who is Professor of Radiation Oncology Emeritus at Harvard Medical School, was an early pioneer in the development of image-based treatment planning and has been responsible for developing and putting into clinical practice such widely used tools as: digitally reconstructed radiographs, dose-volume histograms, and beam's-eye view and has been a leader in the development of proton beam therapy.

Michael Goitein, Ph.D., is Professor of Radiation Therapy Emeritus (Radiation Biophysics) Harvard Medical School.  He is certified in Therapeutic Radiological Physics by the American Board of Radiology and in Medical Physics by the Swiss Society of Medical Physics and Biology. He is also a Fellow in the American Association of Physicists in Medicine and an Honorary Member of the Belgian Society of Radiotherapy and Oncology.

PREFACE 6
CONTENTS 10
1. RADIATION IN THE TREATMENT OF CANCER 12
2. UNCERTAINTY 23
3. MAPPING ANATOMY 33
4. DESIGNING A TREATMENT BEAM 67
5. BIOLOGY MATTERS 95
6. DESIGNING A TREATMENT PLAN 121
7. MOTION MANAGEMENT 148
8. PLANNING MANUALLY 165
9. IMRT and “OPTIMIZATION” 184
10. PROTON THERAPY IN WATER 218
11. PROTON THERAPY IN THE PATIENT 253
12. QUALITY ASSURANCE 293
13. CONFIDENCE 295
AFTERWORD 309
ACKNOWLEDGEMENTS 312
ACRONYMS 313
REFERENCES 315
INDEX 326

Erscheint lt. Verlag 14.8.2007
Reihe/Serie Biological and Medical Physics, Biomedical Engineering
Biological and Medical Physics, Biomedical Engineering
Zusatzinfo XII, 330 p. 120 illus., 40 illus. in color.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Naturwissenschaften Biologie
Naturwissenschaften Physik / Astronomie Angewandte Physik
Naturwissenschaften Physik / Astronomie Quantenphysik
Technik Bauwesen
Schlagworte Cancer • Imaging • Magnetic Resonance Imaging (MRI) • medical physics • Radiation • Radiation damage • radiation oncology
ISBN-10 0-387-72645-4 / 0387726454
ISBN-13 978-0-387-72645-8 / 9780387726458
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