Oxygen Transport to Tissue XXVIII (eBook)

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2007 | 2008
XIV, 216 Seiten
Springer US (Verlag)
978-0-387-71764-7 (ISBN)

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This multidisciplinary book covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism as discussed at the 33rd Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT) held in Australia in 2005. Special attention is paid to methods of oxygen measurement in living tissue and the application of these technologies to understanding the physiological and biochemical basis for pathology related to tissue oxygenation.


At the beginning of a Southern Hemisphere Autumn, the ISOTT tribe assembled for its annual corroboree on the banks of the Brisbane River in Australia for five days of exciting science. Some of the tribe had travelled from as far as Sweden and other parts of Europe; many had spirited themselves across the Pacific Ocean from the Americas. Yet another small contingent had paddled down from Japan. All came with message sticks from their camp-sites. The conference opened with an outdoor barbecue at the Southbank precinct, with the stars of the Southern Cross painting the river on one side and the artificial beach on the other; a perfect venue to meet old friends and to welcome new ones as a cool breeze wafted over our fires. For the next five days there was the usual focus on oxygen; measurement techniques, its role in cancer and other diseases that beset us mortals and the biochemistry and physiology of this small vital molecule. It still astounds many that we have not yet learnt everything there is to know about this valuable friend, albeit a dangerous foe. Time was found for us to visit Australia Zoo and stand in awe before exhibits of Australia's wild-life; great vicious creatures unchanged from the age of the dinosaurs, poisonous snakes and spiders, and gentle marsupials that posed for our digital cameras.

PANEL OF REVIEWERS 8
PREFACE 9
TABLE OF CONTENTS 10
ANTICOAGULANT BLOOD FACTOR DEFICIENCIES ( PROTEIN C) 14
HEMORHEOLOGICAL ASPECTS IN THE MICROVASCULATURE OF SEVERAL PATHOLOGIES 20
CLONIDINE ELICITS A LONG-TERM DEPRESSION IN MUCOSAL RED CELL FLUX 29
REAL-TIME, AUTOMATED, FLUOROPHORE MEDIATED MULTI- CARDIAC MARKER BIOSENSING SYSTEM WITH NANO- METALLIC PARTICLE REAGENT 35
PTEN AND NDUFB8 ABERRATIONS IN CERVICAL CANCER TISSUE 42
PREDICTION OF SURGICAL SITE INFECTIONS AFTER MAJOR SURGERY USING VISIBLE AND NEAR- INFRARED SPECTROSCOPY 48
APPLICATION OF NOVEL METAL NANOPARTICLES AS OPTICAL/ THERMAL AGENTS IN OPTICAL MAMMOGRAPHY AND HYPERTHERMIC TREATMENT FOR BREAST CANCER 56
POSSIBLE MECHANISMS OF IMPROVED 64
EFFECT OF pH AND IMIDAZOLE ON PROTEIN C PURIFICATION FROM COHN FRACTION IV- 1 BY IMAC 71
PREDICTING MELANOMA METASTATIC POTENTIAL BY OPTICAL AND MAGNETIC RESONANCE IMAGING 77
ANALYSIS OF SDHD AND MMP12 IN AN AFFECTED SOLAR KERATOSIS AND CONTROL COHORT 89
WYMAN’S EQUATION AND OXYGEN FLUX THROUGH THE RED CELL 96
SIMULTANEOUS MEASUREMENT OF pO2 AND PERFUSION IN THE RABBIT KIDNEY IN VIVO 102
PSEUDOGENES AND THE ELECTRON TRANSPORT CHAIN 109
INTRATUMORAL VEGF AND FGF1 ADMINISTRATION ALTERS TUMOR GROWTH, VASCULAR DENSITY, OXYGENATION, AND EXPRESSION OF MCP- 1 AND INTERLEUKINS 116
NITRIC OXIDE IN THE KIDNEY Direct measurements of bioavailable renal nitric oxide 124
SEPARATION OF PROTEIN C FROM COHN FRACTION IV- 1 BY MINI- ANTIBODY 131
THE ROLE OF ATP SENSITIVE CHANNELS THE IMPLICATIONS HYPOGLYCAEMIA OF INFANCY ( PHHI) IN INSULIN SECRETION AND IN PERSISTENT HYPERINSULINEMIC 138
TRIPTOLIDE ALTERS MITOCHONDRIAL FUNCTIONS 144
IMMUNOHISTOCHEMICAL IDENTIFICATION AND LOCALIZATION OF ENDOGENOUS ENDOSTATIN AND ITS RELATED PEPTIDES IN MURINE TUMORS 152
IMPACT OF HYPOXIC AND ACIDIC EXTRACELLULAR CONDITIONS ON CYTOTOXICITY OF CHEMOTHERAPEUTIC DRUGS 159
BRIEF EXPOSURE TO –2 GZ REDUCES CEREBRAL OXYGENATION IN RESPONSE TO STAND TEST 166
NORMAL CARDIAC OUTPUT, OXYGEN DELIVERY AND OXYGEN EXTRACTION 172
NEAR INFRA-RED SPECTROSCOPY AND ARTERIAL OXYGEN EXTRACTION AT ALTITUDE 186
OXYGEN DELIVERY AT SEA LEVEL AND ALTITUDE ( AFTER SLOW ASCENT TO 5000 METERS), AT REST AND IN MILD EXERCISE 193
INCREASED SENSITIVITY TO TRANSIENT GLOBAL ISCHEMIA IN AGING RAT BRAIN 200
SINGLE BREATH TRACING FOR CARBON DIOXIDE IN SEPTIC PATIENTS WITH TISSUE HYPOXIA 208

Erscheint lt. Verlag 11.8.2007
Reihe/Serie Advances in Experimental Medicine and Biology
Advances in Experimental Medicine and Biology
Zusatzinfo XIV, 216 p.
Verlagsort New York
Sprache englisch
Themenwelt Medizinische Fachgebiete Innere Medizin Pneumologie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Studium Querschnittsbereiche Infektiologie / Immunologie
Naturwissenschaften Biologie Biochemie
Technik
Schlagworte ATP • Infections • Metabolism • Physiology • Surgery • tissue
ISBN-10 0-387-71764-1 / 0387717641
ISBN-13 978-0-387-71764-7 / 9780387717647
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