Neuroendocrine Correlates of Sleep/Wakefulness (eBook)

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2010 | 2005
XXI, 627 Seiten
Springer US (Verlag)
978-0-387-23692-6 (ISBN)

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Neuroendocrine Correlates of Sleep/Wakefulness
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As the title suggests, and unlike other existing books on sleep medicine, Neuroendocrine Correlates of Sleep/Wakefulness will be devoted primarily to endocrine regulation of the behavioral state control. It will address a wide spectrum of sleep./wakefulness phenomena (both animals and humans), including pathogenesis, diagnosis, and management.

 

From molecular biology to applied clinical therapy, sleep research has been transformed in the last few years from a research backwater to an important interdisciplinary field.

Anyone who regularly reads the literature on sleep, biological rhythms, or neuroendocrinology is aware that one of the subspecialties within sleep medicine, the neuroendocrine correlates of sleep/wakefulness, has in particular experienced a growth rate that is even faster than that of the field as a whole. To a significant extent this has been due to the introduction of new research technologies.

The widespread adoption of a range of new methods in sleep research has opened a window into activities at the cellular and molecular level, which previously had been tightly closed. Consequently these activities are being characterized with a degree of precision and sensitivity that is without precedent. This volume invites the reader to explore the new vistas that have been opened onto the neuroendocrine frontier of sleep medicine. The editors have selectively identified a number of key articles having a citation frequency, which is considerably above the norm or which otherwise have contributed importantly to defining the neuroendocrine perspective.

This new volume on Neuroendocrine Correlates of Sleep/Wakefulness is an up-to-date resource of research summaries and reviews written by major contributors to the fields of sleep, biological rhythms and neuroendocrinology. Its coverage is broad and its basic

and clinical science reviews are detailed.

In this volume, an international team of experts discuss their latest ideas, concepts, methods, and interpretations with supporting examples. This volume is intended for advanced students and specialists in psychobiology, neuroscience, neuroendocrinology, and psychiatry but might also be interest to anyone concerned with understanding the Neuroendocrine correlates of sleep/wakefulness.

The contributions are directed more towards providing an integrated view of the field from the perspective of the authors, rather than being a compendium of recent results. The intent is to provide a reference book for recent and future workers in this and related areas of medicine and biology. Each topic in this volume has received the attention of a panel of authors who have responded to our request to review and place into perspective the major issues, which will undoubtedly confront newcomers to the field.

The topics dealt with in Neuroendocrine correlates of Sleep/wakefulness are both diverse and complex. The editors hope that this volume will provide an authoritative summary of important issues in the neuroendocrine correlates of sleep/wakefulness. We also hope that it will motivate new researchers to join the quest for solutions to the problems that have been identified by our contributing authors.


As the title suggests, and unlike other existing books on sleep medicine, Neuroendocrine Correlates of Sleep/Wakefulness will be devoted primarily to endocrine regulation of the behavioral state control. It will address a wide spectrum of sleep./wakefulness phenomena (both animals and humans), including pathogenesis, diagnosis, and management. From molecular biology to applied clinical therapy, sleep research has been transformed in the last few years from a research backwater to an important interdisciplinary field. Anyone who regularly reads the literature on sleep, biological rhythms, or neuroendocrinology is aware that one of the subspecialties within sleep medicine, the neuroendocrine correlates of sleep/wakefulness, has in particular experienced a growth rate that is even faster than that of the field as a whole. To a significant extent this has been due to the introduction of new research technologies. The widespread adoption of a range of new methods in sleep research has opened a window into activities at the cellular and molecular level, which previously had been tightly closed. Consequently these activities are being characterized with a degree of precision and sensitivity that is without precedent. This volume invites the reader to explore the new vistas that have been opened onto the neuroendocrine frontier of sleep medicine. The editors have selectively identified a number of key articles having a citation frequency, which is considerably above the norm or which otherwise have contributed importantly to defining the neuroendocrine perspective. This new volume on Neuroendocrine Correlates of Sleep/Wakefulness is an up-to-date resource of research summaries and reviews written by major contributors to the fields of sleep, biological rhythms and neuroendocrinology. Its coverage is broad and its basic and clinical science reviews are detailed. In this volume, an international team of experts discuss their latest ideas, concepts, methods, and interpretations with supporting examples. This volume is intended for advanced students and specialists in psychobiology, neuroscience, neuroendocrinology, and psychiatry but might also be interest to anyone concerned with understanding the Neuroendocrine correlates of sleep/wakefulness. The contributions are directed more towards providing an integrated view of the field from the perspective of the authors, rather than being a compendium of recent results. The intent is to provide a reference book for recent and future workers in this and related areas of medicine and biology. Each topic in this volume has received the attention of a panel of authors who have responded to our request to review and place into perspective the major issues, which will undoubtedly confront newcomers to the field. The topics dealt with in Neuroendocrine correlates of Sleep/wakefulness are both diverse and complex. The editors hope that this volume will provide an authoritative summary of important issues in the neuroendocrine correlates of sleep/wakefulness. We also hope that it will motivate new researchers to join the quest for solutions to the problems that have been identified by our contributing authors.

In Memoriam 6
Preface 8
Acknowledgments 9
Contents 11
List of Contributors 14
Basic Sciences 19
The Developmental Regulation of Wake/ Sleep System 20
Basic Mechanisms of Circadian Rhythms and their Relation to the Sleep/Wake Cycle 36
The Neuroendocrine Loop Model Revisited: Is It Valid or Even Relevant? 58
Biological Rhythms in Neuroendocrinology 76
Biological Clock Control of Glucose Metabolism Timing Metabolic Homeostasis 104
Molecular Mechanisms of Melatonin Action: Targets in Sleep Regulation 135
Serotonin and Neuroendocrine Regulation Relevance to the Sleep/ Wake Cycle 152
Locus Coeruleus and Adrenergic Modulation of Rapid Eye Movement Sleep 177
Neuroendocrine Outcomes of Sleep Deprivation in Humans and Animals 193
Sleep- Inducing Substances in the Regulation of Sleep 214
The Influence of Orexin on Sleep and Wakefulness 233
Clinical Sciences 253
The Development and Regulation of Expressed Rhythmicity in Infants 254
Sleep and Circadian Rhythm of Melatonin in Smith- Magenis Syndrome 269
Melatonin in Circadian Rhythm Sleep Disorders 278
The Role of Melatonin in Sleep Regulation 304
Sleep and Circadian Rhythms in the Blind 319
Disturbances of Hormonal Circadian Rhythms in Shift Workers 332
Melatonin, The Pineal Gland, and Headache Disorders 361
The Role of Peptides in Disturbed Sleep in Depression 374
Neuroendocrine Correlates of Sleep in Premenstrual, Pregnant, Postpartum and Menopausal Depression 396
Neuroendocrine and Behavioral Correlates of Sleep Deprivation: A Synthesis of Neurobiological and Psychological Mechanisms 417
Endocrine Changes in Male Patients with Obstructive Sleep Apnea 427
Sleep-Disordered Breathing and Hormones 440
Autonomic Nervous System Activity during Sleep in Humans. Heart Rate Variability during Sleep 474
Neuroendocrine Correlates of Infectious Disease: Implications for Sleep 489
Neuroendocrine Correlates of Restless Legs Syndrome 501
Neuroendocrine and Neuroimmune Correlates of Narcolepsy 514
Sleep Disorders and Neuroendocrine Investigations An Arctic Perspective 529
Role of Pro- Inflammatory Cytokines In Sleep Disorders 537
Sleep and Circadian Neuroendocrine Function in Seasonal Affective Disorder 553
Index 588

Erscheint lt. Verlag 14.3.2010
Mitarbeit Stellvertretende Herausgeber: Daniel P. Cardinali, S. R. Pandi-Perumal
Zusatzinfo XXI, 627 p.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Innere Medizin
Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
Technik
Schlagworte attention • Cardinali • Correlates • homeostasis • nervous system • Neuroendocrine • Neuroendocrinology • Neuroscience • Psychiatry • Sleep • wakefulness
ISBN-10 0-387-23692-9 / 0387236929
ISBN-13 978-0-387-23692-6 / 9780387236926
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