Robotic Radiosurgery. Treating Tumors that Move with Respiration (eBook)

Foreword 5
Introduction 9
Contents 13
Author Index 16
Respiration Motion and Tumor Tracking Techniques 17
Tumor Motion Ranges Due to Respiration and Respiratory Motion Characteristics 18
Respiratory Motion Tracking for Robotic Radiosurgery 29
Patient Alignment and Target Tracking in Radiosurgery of Soft- Tissue Tumors Using Combined Fiducial and Skeletal Structures Tracking Techniques 44
Thoraco-Abdominal Dosimetry, Radiobiology, and Imaging 50
The Radiobiological Rationale for Hypofractionation of Lung and Liver Tumors 51
18FDG-PET/CT for Treatment Planning and Follow-Up 66
Treatment Planning of Abdominal Lesions 73
Use of a Target Complexity Index in Radiosurgical Plan Evaluation 85
Dose Escalation with the Frameless Respiratory Tumor Tracking System of the CyberKnife for Early Stage Non- Small- Cell Lung Cancer 91
Thoraco-Abdominal Fiducial Placement Strategies 98
Percutaneous Placement of Fiducial Markers for Thoracic Malignancies 99
Use of a Blood Patch Technique to Prevent Pneumothorax During Insertion of Lung Fiducials 109
Thoracic Fiducial Placement via Flexible Bronchoscopy 112
Endoscopic Ultrasound– Guided Fiducial Placement for CyberKnife Radiosurgery 118
Lung Tumor Treatment – Techniques and Experiment 122
Stereotactic Body Radiation Therapy in the Treatment of Early Stage Non- Small Cell Lung Cancer 123
Dosimetric Considerations for Stereotactic Body Radiotherapy Delivery in the Lung 130
Selection of Treatment for Patients with Early Stage Non- Small Cell Lung Cancer in a Multidisciplinary Thoracic Oncology Program 138
CyberKnife Frameless Image- Guided High- Dose Fractionated Stereotactic Radiosurgery with the Synchrony Motion Tracking Module in the Treatment of Single Small Peripheral Lung Tumors 150
Initial Experience Treating Lung Tumors with the CyberKnife 159
Stereotactic Radiosurgery for Early Stage Non- Small Cell Lung Cancer: Rationale, Patient Selection, Results and Complications 168
Toxicity and Efficacy of Treating Mediastinal and Hilar Lesions 179
Liver and Pancreas Treatment – Techniques and Experiment 195
A Review of Stereotactic Body Radiotherapy for Liver and Pancreas 196
Multidisciplinary Overview of Local- Regional Therapies for Liver Malignancies 205
Stereotactic Radiosurgery for Liver Malignancies Using the CyberKnife 216
CyberKnife Radiosurgery for Pancreatic Cancer 225
Stereotactic Radiosurgery for Unresectable Adenocarcinoma of the Pancreas: Initial Experience at Sinai Hospital of Baltimore 238
Emerging Thoraco-Abdominal Radiosurgery Concepts 244
4D Treatment Optimization and Planning for Radiosurgery with Respiratory Motion Tracking 245
Xsight Lung Tracking System: A Fiducial- Less Method for Respiratory Motion Tracking 261
CyberKnife Radiosurgery: Quality of Life and Cost Considerations 279
Abbreviations 290
Subject Index 292
List of Contributors 304