The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes (eBook)

Volume I: Neuropsychological Endophenotypes and Biomarkers

Michael Ritsner (Herausgeber)

eBook Download: PDF
2009 | 2009
XIV, 273 Seiten
Springer Netherland (Verlag)
978-1-4020-9464-4 (ISBN)

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Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer's disease, epilepsy, alcoholism, substance abuse and others are some of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances.

This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: 'Neuropsychological Endophenotypes and Biomarkers' (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), 'Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers', 'Metabolic and Peripheral Biomarkers' and 'Molecular Genetic and Genomic Markers'. The contributors are internationally and nationally recognized researchers and experts from 16 countries.

This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.


Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer's disease, epilepsy, alcoholism, substance abuse and others are some of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances.This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: "e;Neuropsychological Endophenotypes and Biomarkers"e; (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), "e;Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers"e;, "e;Metabolic and Peripheral Biomarkers"e; and "e;Molecular Genetic and Genomic Markers"e;. The contributors are internationally and nationally recognized researchers and experts from 16 countries.This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.

Ritsner_Vol 1_FM.pdf 2
Ritsner_Ch01.pdf 15
Ritsner_Ch02.pdf 35
Ritsner_Ch03.pdf 52
Ritsner_Ch04.pdf 68
Ritsner_Ch05.pdf 98
Ritsner_Ch06.pdf 114
Ritsner_Ch07.pdf 123
Ritsner_Ch08.pdf 133
Ritsner_Ch09.pdf 150
Ritsner_Ch10.pdf 164
Ritsner_Ch11.pdf 172
Ritsner_Ch12.pdf 186
Ritsner_Ch13.pdf 203
Ritsner_Ch14.pdf 219
Ritsner_Ch15.pdf 229
Ritsner_Ch16.pdf 235
Ritsner_Ch17.pdf 246
Ritsner_Vol 1_BM.pdf 266
Ritsner_Vol 1_Index.pdf 277

Erscheint lt. Verlag 21.4.2009
Zusatzinfo XIV, 273 p.
Verlagsort Dordrecht
Sprache englisch
Themenwelt Geisteswissenschaften
Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Medizin / Pharmazie Medizinische Fachgebiete Psychiatrie / Psychotherapie
Studium 2. Studienabschnitt (Klinik) Humangenetik
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
Schlagworte Alzheimer • Biomarkers • Bipolar Disorder • Emotion • Endophenotype • genes • Mood Disorder • Neurology • Neuroscience • Phenotype • Proteomics • Psychiatric Disorder • Psychiatry • Translation
ISBN-10 1-4020-9464-7 / 1402094647
ISBN-13 978-1-4020-9464-4 / 9781402094644
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