Programmed Cell Death in Cancer Progression and Therapy (eBook)

Introduction Chapter 1: Cell Death: History and Future by Zahra Zakeri and Richard A. Lockshin Chapter 2: Caspase Mechanisms by Guy S. Salvesen and Stefan J. Riedl Chapter 3: The Mitochondrial Death Pathway by Anas Chalah and Roya Khosravi-Far Chapter 4: Apoptotic Pathways in Tumor Progression and Therapy by Armelle Melet, Keli Song, Octavian Bucur , Zainab Jagani, Alexandra R. Grassian and Roya Khosravi-Far Chapter 5: Therapeutic Targeting of Death Pathways in Cancer - Mechanisms for activating cell death in cancer cells by Ting-Ting Tan and Eileen White Chapter 6: Overcoming Resistance to Apoptosis in Cancer Therapy by Peter Hersey, X.D. Zhang, N. Mhaidat Chapter 7: TRAIL Receptors: Targets for Cancer Therapy by Robin C. Humphreys and Wendy Halpern Chapter 8: Rational Design of Therapeutics Targeting the Bcl-2 Family - Are some cancer cells primed for death but waiting for a final push? by Victoria Del Gaizo Moore and Anthony Letai Chapter 9: Autophagy and Tumor Suppression - Recent advances in understanding the link between autophagic cell death pathways and tumor development by Shani Bialik and Adi Kimchi Chapter 10: Regulation of Programmed Cell Death by the p53 Pathway by Kageaki Kuribayashi and Wafik S. El-Deiry Chapter 11: Regulation Of Programmed Cell Death by Nf-k B and its Role in Tumorigenesis and Therapy by Yongjun Fan, Jui Dutta, Nupur Gupta, Gaofeng Fan and Céline Gélinas Chapter 12: Targeting Proteasomes as Therapy in Multiple Myeloma by Dharminder Chauhan, Teru Hideshima and Kenneth C. Anderson Chapter 13: Histone Deacetylase Inhibitors: Mechanisms and Clinical Significance in Cancer - HDAC inhibitor-induced apoptosis by Sharmila Shankar and Rakesh K. Srivastava Chapter 14: RNA Interference and Cancer: Endogenous Pathways and Therapeutic Approaches by Derek M. Dykxhoorn, Dipanjan Chowdhury, Judy Lieberman Chapter 15:Cancer Stem Cells and Impaired Apoptosis by Zainab Jagani and Roya Khosravi-Far