Dynamics of Bone and Cartilage Metabolism

John P. Bilezikian, MD, the Dorothy L. and Daniel H. Silberberg Professor of Medicine and Professor of Pharmacology at the College of Physicians & Surgeons, Columbia University is Chief of the Division of Endocrinology and Director of the Metabolic Bone Diseases Program at Columbia University Medical Center. Dr. Bilezikian received his undergraduate training at Harvard College and his medical training at the College of Physicians & Surgeons. He completed four years of house staff training (internship, residency and Chief Residency) on the Medical Service at Columbia Presbyterian Medical Center. Dr. Bilezikian received his training in Metabolic Bone Diseases and in Endocrinology at the NIH in the Mineral Metabolism Branch under the tutelage of Dr. Gerald Aurbach. Dr. Bilezikian belongs to a number of professional societies including the American Society for Bone and Mineral Research, of which he served as President, 1995-1996 and the International Society of Clinical Densitometry, of which he served as President, 1999-2001. He serves on the Board of Governors of the International Osteoporosis Foundation (1998-present) and on its Committee of Scientific Advisors (2001-present). He is Chair of the Endocrine Fellows Foundation. He served as Editor-in-Chief of the Journal of Clinical Endocrinology and Metabolism (2000-2004) and as Senior Associate Editor of the Journal of Bone and Mineral Research (2008-2012). He is Executive Advisory Editor of Bone Research (2013-present). His books include Editor-in-Chief of The Parathyroids [1994, 2001, 2014], and co-editor of The Aging Skeleton (1999), Dynamics of Bone and Cartilage Metabolism (1999, 2006), Principles of Bone Biology (1996, 2002, 2008) and Osteoporosis in Men (2010). He served as co-chair of the last three NIH Workshops on Primary Hyperparathyroidism (2002, 2008, 2013). He is the recipient of the Distinguished Physician Award of the Endocrine Society, the Frederic C. Bartter Award of the American Society for Bone and Mineral Research (ASBMR) for Excellence in Clinical Research and the First Annual Global Leadership Award of the International Society of Clinical Densitometry. In 2009, he received the Gideon A. Rodan Excellence in Mentorship Award from the ASBMR. He received the Laureate Distinguished Educator Award of The Endocrine Society in 2014. In 2014, he was made honorary member of the Brazilian Society of Endocrinology and Metabolism. His publications number over 700. Markus J Seibel, MD PhD FRACP FAHMS, is Professor of Endocrinology at Sydney Uni¬versity. He is the Inaugural Director of the Bone Research Program at the ANZAC Research Institute, and heads the Department of Endocrinology & Meta¬bolism at Concord Hospital, Sydney. His research in musculoskeletal biology covers topics such as glucocorticoid signalling in bone and its effects on bone and systemic fuel metabolism and ageing; the biology of bone metastases; and the clinical efficacy of secondary fracture prevention programs. Prof Seibel has published over 400 scientific papers and is the editor of 8 books. In 2017, he has been elected to the Australian Academy of Health and Medical Sciences. Prof Seibel is a Past President of the Australia and New Zealand Bone & Mineral Society (ANZBMS), a Member of the Board of Directors, International Federation of Musculoskeletal Research Societies (IFMRS), and the Chair of the Australian National Alliance for Secondary Fracture Prevention.

K. von der Mark, Structure and Biosynthesis of Collagens.
S.P. Robins, Fibrillogenesis and Maturation of Collagens.
C.M. Gundberg and K. Nishimoto, Vitamin K Dependent Proteins of Bone and Cartilage.
D. Heinegard, T. Saxne, and P. Lorenzo, Non-Collagenous Proteins: Glycoproteins and Related Molecules.
T.E. Hardingham, Proteoglycans and Glycosaminoglycans.
G. Russell and P. Croucher, Regulatory Components: Growth Factors.
L. Raisz and J. Lorenzo, Cytokines and Prostaglandins.
M.H. Helfrich and M.A. Horton, Integrins and Adhesion Molecules.
P. Henthorn, P. Leboy, and J.L. Millán, Acid and Alkaline Phosphatases.
I.M. Clark and G. Murphy, Matrix Proteases.
A.L. Boskey, Mineralization, Structure, and Function of Bone.
J.B. Lian and G. Stein, The Cells of Bone.
L.A. Fitzpatrick and J.P. Bilezikian, Parathyroid Hormone.
D. Goltzman and A.C. Karaplis, Structure and Metabolism of the Extracellular Matrix of Bone and Cartilage: PTHrP: Of Molecules, Mice, and Men.
R. Bouillon, Structure and Metabolism of the Extracellular Matrix of Bone and Cartilage: Vitamin D.
S. Khosla and B.L. Riggs, Structure and Metabolism of the Extracellular Matrix of Bone and Cartilage: Sex and Steroid Effects on Bone Metabolism.
R. Rizzoli and J.-P. Bonjour, Structure and Metabolism of the Extracellular Matrix of Bone and Cartilage: Physiology of Calcium and Phosphate Homeostasis.
D.W. Dempster, Structure and Metabolism of the Extracellular Matrix of Bone and Cartilage: New Concepts in Bone Remodeling.
J. Risteli and L. Risteli, Structure and Metabolism of the Extracellular Matrix of Bone and Cartilage: Products of Bone Collagen Metabolism.
P. Bruckner and E.F. Eikenberry, Structure and Metabolism of the Extracellular Matrix of Bone and Cartilage: Supramolecular Structure of Cartilage Matrix.
M.T. Bayliss, Structure and Metabolism of the Extracellular Matrix of Bone and Cartilage: Physiology and Pathology of Cartilage Metabolism.
D.-H. Manicourt, Structure and Metabolism of the Extracellular Matrix of Bone and Cartilage: Products of Cartilage Metabolism.
P.A. Simkin, Fluid Dynamics of the Joint Space Trafficking of Matrix Breakdown Products.
H.J. Häuselmann, In Vitro Models of Cartilage Metabolism.
R.D. ALtman and C.J. Lozada, Animal Models of Cartilage Breakdown.
H.A.P. Pols, J.P.T.M. van Leeuwen, and A.G. Uitterlinden, Genetic Approaches to Metabolic Bone Disease.
H. Schmidt-Gayk, Measurement of Local and Systemic Regulators of Bone Metabolism.
R. Eastell and K.E. Naylor, Measurement of Biochemical Markers of Bone Formation.
M.E. Kraenzlin and M.J. Seibel, Measurement of Biochemical Markers of Bone Resorption.
E.F. Eriksen and K. Brixen, Validation of Local and Systematic Markers of Bone Turnover.
S. Gay, M. Neidhart, and R.E. Gay, Genetic Markers of Joint Disease.
E.J. Thonar, M.E. Lenz, K. Masuda, and D.-H. Manicourt, Markers of Cartilage Metabolism.
P.J. Delmas and P. Garnero, Postmenopausal Osteoporosis.
C. Rosen, Age-Related Osteoporosis.
E.S. Orwoll, Osteoporosis in Men.
I.R. Reid, Steroid Induced Osteoporosis.
E. Shane, Secondary Osteoporosis.
M.K. Drezner, Osteomalacia and Rickets.
K.J. Martin and E.A. Gonzalez, Renal Osteodystrophy.
S.J. Silverberg and J.P. Bilezikian, Primary Hyperparathyroidism.
A. Grauer and E.S. Siris, Paget's Disease of Bone.
J.-J. Body, Metastatic Bone Disease.
M.P. Whyte, Rare Bone Diseases.
S.R. Goldring and M.B. Goldring, Rheumatoid Arthritis and Other Inflammatory Joint Pathologies.
K. Akesson, Osteoarthritis and Degenerative Spine Pathologies.
J.M. Gertner, Normal and Abnormal Growth and Development.