Biological Inorganic Chemistry - Robert R. Crichton

Biological Inorganic Chemistry

A New Introduction to Molecular Structure and Function
Buch | Softcover
472 Seiten
2012 | 2nd edition
Elsevier Science Ltd (Verlag)
978-0-444-53782-9 (ISBN)
82,25 inkl. MwSt
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An increasing understanding of the importance of metals in biology, the environment and medicine, and the multiple roles of metal ions in biological systems, has given rise to biological inorganic chemistry as a field of study. The book begins with an overview of the concepts, chemical and biological, required for the analysis which follows.
Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Second Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. Beginning with an overview of metals and selected nonmetals in biology, the book then discusses the following concepts: basic coordination chemistry for biologists; structural and molecular biology for chemists; biological ligands for metal ions; intermediary metabolism and bioenergetics; and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment.

Robert Crichton is Emeritus Professor, Faculty of Science, Universite Catholique de Louvain in Belgium. He has some forty years experience in teaching the subject, and published over 200 scientific articles and a number of books. Since 1985 he has organized a series of over twenty advanced courses on Metals in Biology in Louvain-la-Neuve, which have trained over 1300 doctoral and post-doctoral students, many of whom are today leaders in the field. The Second Edition of Biological Inorganic Chemistry: An Introduction to Molecular Structure and Function received the 2013 TEXTY Textbook Excellence Award in Physical Sciences from the Text and Academic Authors Association.

1. An Overview of Metals and Selected Nonmetals in Biology2. Basic Coordination Chemistry for Biologists3. Structural and Molecular Biology for Chemists4. Biological Ligands for Metal Ions5. An Overview of Intermediary Metabolism and Bioenergetics6. Methods to Study Metals in Biological Systems7. Metal Assimilation Pathways8. Transport, Storage, and Homeostasis of Metal Ions9. Sodium and Potassium – Channels and Pumps10. Magnesium–Phosphate Metabolism and Photoreceptors11. Calcium – Cellular Signalling12. Zinc – Lewis Acid and Gene Regulator13. Iron14. Copper – Coping with Dioxygen15. Nickel and Cobalt16. Manganese – Oxygen Generation and Detoxification17. Molybdenum, Tungsten, Vanadium, and Chromium18. Non-metals in Biology19. Biomineralisation20. Metals in Brain21. Metals and Neurodegeneration22. Metals in Medicine and Metals as Drugs23. Metals in the Environment

Verlagsort Oxford
Sprache englisch
Maße 191 x 235 mm
Themenwelt Naturwissenschaften Chemie Anorganische Chemie
ISBN-10 0-444-53782-1 / 0444537821
ISBN-13 978-0-444-53782-9 / 9780444537829
Zustand Neuware
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