Nanostructured Biomaterials for Overcoming Biological Barriers

M.J. Alonso has a long-track record of experience (more than 25 years) in the development of nanocarriers for overcoming biological barriers. Her contributions have not only been scientifically relevant (200 publications, more than 30 relevant projects) but have also led to several patents and to the development of a product under clinical evaluation. Noemi Stefania Csaba holds a research and teaching position at the University of Santiago de Compostela at the Department of Pharmaceutical Technology, Nanobiofar Group. She obtained her PhD Degree in 2005 at the University of Santiago de Compostela in the field of nanomedicine and nanotechnology and worked as a post-doctoral research fellow at the Swiss Federal Institute of Technology (ETH Zurich, 2005-2007). Noemi Csaba is the author of more than 20 scientific articles published in internationally recognised journals, several book chapters, two patents and more than 30 presentations and international symposia. Her main research interests and expertise are vaccine delivery, gene therapy, targeted nanocarriers , nanotechnology and nanomedicine in cancer research.

Preface;

Introduction: an historical perspective;

Nanostructures overcoming the intestinal barrier;

Nanostructures overcoming the nasal barrier;

Nanostructures overcoming the ocular barrier;

Nanostructures overcoming the pulmonary barrier;

Nanostructures overcoming the skin barrier;

Nanostructures overcoming the blood brain barrier;

The biological barriers related to parental drug delivery;

Drug delivery in tissue engineering;

Clinically relevant case studies;

Regulatory aspects;

Nanotechnology for the development of new global therapeutic strategies;

Concluding remarks;

Index