Neural Cell Transplantation

Introductory Reviews.- Neural Transplantation and Stem Cells.- Adult Stem Cells for the Treatment of Neurological Disease.- Human Trials for Neurodegenerative Disease.- Practical/Methodological Chapters.- Differentiation of Neuroepithelia from Human Embryonic Stem Cells.- Derivation of High-Purity Oligodendroglial Progenitors.- Flow Cytometric Characterization of Neural Precursor Cells and Their Progeny.- Isolation, Expansion, and Differentiation of Adult Mammalian Neural Stem and Progenitor Cells Using the Neurosphere Assay.- Human Mesenchymal Stem Cell Culture for Neural Transplantation.- Umbilical Cord Blood Cells.- Animal Models of Neurodegenerative Diseases.- Animal Models of Multiple Sclerosis.- Transplantation of Oligodendrocyte Progenitor Cells in Animal Models of Leukodystrophies.- A Rat Middle Cerebral Artery Occlusion Model and Intravenous Cellular Delivery.- MR Tracking of Stem Cells in Living Recipients.- Identifying Neural Progenitor Cells in the Adult Brain.- Immune Ablation Followed by Autologous Hematopoietic Stem Cell Transplantation for the Treatment of Poor Prognosis Multiple Sclerosis.

From the reviews:

“In this book, the authors discuss the current understanding of the management of degenerative diseases of the CNS. … Neurologists, neurosurgeons, neurophysiologists, and neuroscientists are the intended audience. … the book flows easily and describes the most common research and technical protocols associated with human stem cell handling and separation. It is a well-referenced and illustrated book and worth its value for most labs … . a good book for neuroscientists who are directly involved in the separation and production of human stem cells.” (Celso Agner, Doody’s Review Service, December, 2009)