Advances in Microbial Physiology

Professor Robert Poole is West Riding Professor of Microbiology at the University of Sheffield. He has >35 years’ experience of bacterial physiology and bioenergetics, in particular O2-, CO- and NO-reactive proteins, and has published >300 papers (h=48, 2013). He was Chairman of the Plant and Microbial Sciences Committee of the UK Biotechnology and Biological Sciences Research Council and has held numerous grants from BBSRC, the Wellcome and Leverhulme Trusts and the EC. He coordinates an international SysMO systems biology consortium. He published pioneering studies of bacterial oxidases and globins and discovered the bacterial flavohaemoglobin gene (hmp) and its function in NO detoxification He recently published the first systems analyses of responses of bacteria to novel carbon monoxide-releasing molecules (CORMs) and is a world leader in NO, CO and CORM research.

Contributors
Geobacter


1. Introduction
2. Distribution and Abundance of Geobacter Species
3. Brief Description of Geobacter Species
4. Phylogeny and Genomic Resources
5. Electron Acceptors
6. Electron Donors
7. Extracellular Electron Transfer
8. Regulation of Metabolism
9. Environmental Systems Biology of Geobacter
10. Biogeochemical Impacts of Geobacter Species
11. Practical Applications of Geobacter Species
12. Conclusions
Acknowledgments

Network Approaches to the Functional Analysis of Microbial Proteins


1. Introduction
2. Network Biology
3. Functional Interaction Networks
4. Functional Analysis
5. Using Networks for Functional Analysis
6. Conclusions

The Diversity of Microbial Responses to Nitric Oxide and Agents of Nitrosative Stress


Abbreviations
1. Overview
2. Historical Perspective
3. Origins of Reactive Nitrosative Species in Biology
4. The Biological Chemistry of NO and Related Species
5. Laboratory Methods
6. Bacterial Responses to RNS: Effectors and Regulators
7. Microbial Sensing of NO and Gene Regulation
8. Global and Systems Approaches to Understanding Responses to NO and RNS
9. Conclusions