CACO-2 Cells & their Uses

Presents topical research in the study of CACO-2 cells and their uses. This book discusses topics that include the application of CACO-2 cell models as a supportive in vitro tool during drug discovery and formulation; co-culture systems with CACO-2 cells to evaluate the bioactivity of plant extracts; and, more.

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CACO-2 cell cultures are widely used in vitro models in several scientific fields such as nutrition, physiopathology, pharmacology, and toxicology. When cultured onto filters, these cells form a highly polarised epithelium that allows discrimination between apical and basolateral compartments. This book presents topical research in the study of CACO-2 cells and their uses. Topics discussed include the application of CACO-2 cell models as a supportive in vitro tool during drug discovery and formulation; co-culture systems with CACO-2 cells to evaluate the bioactivity of plant extracts and the use of CACO-2 cells in intestinal transport, cell-matrix interactions and wound healing in intestinal villus cells.