Biomarkers in Oncology
Springer-Verlag New York Inc.
978-1-4419-9754-8 (ISBN)
A powerful tool for determining decisions on therapy, selecting drug regimens, monitoring the efficacy of treatment, and performing individualized surveillance, biomarkers represent the forefront of cancer research and treatment. As these technologies become increasingly available for clinical use, this book will be an essential resource for oncologists and translational researchers.
Heinz-Josef Lenz, MD, FACP, Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033
Ch. 1: Predictive Markers in Colon Cancer
Armin Gerger, Melissa J. LaBonte, and Heinz-Josef Lenz
Ch. 2: Prognostic Markers in Breast Cancer
Agustin A. Garcia, and Nazish Ahmad
Ch. 3: Predictive Markers in Lung Cancer
Stephen V. Liu, and Barbara J. Gitlitz
Ch. 4: Prostate Cancer: Predictive Markers in Clinical Development
Courtney K. Phillips, and Daniel P. Petrylak
Ch. 5: Biomarkers in GIST
Howard J. Lim, and Charles D. Blanke
Ch. 6: Cytogenetic and Molecular Aberrations as Predictive Biomarkers in Acute Myeloid Leukemia
Steffen Heeg, and Cornelius F. Waller
Ch. 7: Prognostic Markers in Colon Cancer
Janine M. Davies, and Howard L. McLeod
Ch. 8: Markers in Lung Cancer
Edwin Y. Lin, Ravin Rupani, and Barbara J. Gitlitz
Ch. 9: Molecular Markers of Prostate Cancer Outcome
David Ian Quinn, and Gregory P. Swanson
Ch. 10: Prediction of Chemotherapy Toxicities
Pierre Laurent-Puig, Thierry Lecomte, Marie-Anne Loriot, Valerie Boige, and Helene Blons
Ch. 11: Surrogate Markers—The Role of Positron Emission Tomography Scanning
Derek G. Power, and David H. Ilson
Ch. 12: Circulating Tumor Cells as Biomarkers
Amir Goldkorn, Tong Xu, and Stephen V. Liu
Ch. 13: Focus on Personalized Molecular Based Medicine
Lex HT Van der Ploeg, Bud Mishra, Casimir P. Eitner, Jon Burrows, Thomas Wray Tombler, Jr., Vladimir Poponin, Dan J. Knauer, Ilia Ichetovkin, Richard M. Pinnola, Gregory A. Endress, and Patrick Soon-Shiong
Ch. 14: Clinical Validation of Biomarkers
Sumithra J. Mandrekar, and Daniel Sargent
Ch. 15: Regulatory Issues
Maxwell T. Vergo, and Al B. Benson III
Ch. 16: Biomarkers for Safety Assessment and Clinical Pharmacology
Stan Louie, and Jared Russell
Ch. 17: Biomarker Discovery Strategies: DNA, RNA and Protein
Eduardo Vilar, and Josep Tabernero
Ch. 18: Biomarkers For Go/No Go Decisions
Ben Markman, and Josep Tabernero
Zusatzinfo | 32 Tables, black and white; 37 Illustrations, color; 21 Illustrations, black and white; XVI, 447 p. 58 illus., 37 illus. in color. |
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Verlagsort | New York, NY |
Sprache | englisch |
Maße | 155 x 235 mm |
Gewicht | 857 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Medizin / Pharmazie ► Pharmazie | |
Medizin / Pharmazie ► Studium ► 1. Studienabschnitt (Vorklinik) | |
Naturwissenschaften ► Biologie ► Biochemie | |
Schlagworte | Biomarker • Breast • Cancer • Colon • drug development • Lung • Microassay • Oncology • Predictive • Prognostic • Prostate • Surrogate • Toxicity |
ISBN-10 | 1-4419-9754-7 / 1441997547 |
ISBN-13 | 978-1-4419-9754-8 / 9781441997548 |
Zustand | Neuware |
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