The Claisen Rearrangement – Methods and Applications

Martin Hiersemann was born 1966 in Berlin, Germany. He received his Ph.D. in 1995 under the guidance of Johann Mulzer at the Freie Universitat Berlin. After postdoctoral stay with Gary A. Molander at the University of Colorado, he started his independent research at the Dresden University of Technology in the fall of 1997. He was a visiting scientist at the University of Tsukuba in the group of Akira Hosomi in 2002, at Harvard University in the group of David A. Evans in 2003 and at the Montana State University with Paul A. Grieco in 2004. His research activities are concerned with the catalysis of sigmatropic rearrangements as well as natural product synthesis. Udo Nubbemeyer received his Diploma and PhD in the group of Prof. Dr. E. Winterfeldt (University of Hannover) and spent a postdoctoral spell at the Ciba-Geigy Laboratory at the University of Fribourg (Switzerland) with Prof. D. Bellus and Dr. B. Ernst (1989/1990). From 1991 to 1996, he worked on his 'Habilitation' in the group of Prof. Dr. J. Mulzer (Freie Universitat Berlin). Then, he passed an assistant lecturer period in Berlin and a temporary professorship at the TU Dresden (1999/2001). Actually, he works as an associate professor at the Johannes Gutenberg-Universitat of Mainz. His major topics of interest are olefin synthesis, aza Claisen rearrangements, radical cyclizations, medium-sized rings, total synthesis of natural and pharmaceutically important products, alkaloids, eicosanoids, steroids, and amino acids.

Preface Theoretical Aspects of the Claisen Rearrangement Chorismate Mutase-Catalyzed Claisen Rearrangement Chiral Metal Complex-Catalyzed Aliphatic Claisen Rearrangement Alphabetic and Aromatic Claisen Rearrangement Metal-Catalyzed Claisen Rearrangement Simple Enolate and Chelate Enolate Claisen Rearrangement Claisen-Johnson Orthoester Rearrangement The Meerwein-Eschenmoser Claisen Rearrangement The Carroll Rearrangement Thio-Claisen Rearrangement Aza-Claisen Rearrangement