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Polymorphism – In the Pharmaceutical Industry

R Hilfiker (Autor)

Software / Digital Media
433 Seiten
2006
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-60788-4 (ISBN)
239,95 inkl. MwSt
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Emphasizes why solid-state issues are important, which approaches should be taken to avoid problems and exploit the opportunities offered by solid state properties in the pharmaceutical and agricultural industries.
Edited by one of the leading experts in the field, this handbook emphasizes why solid-state issues are important, which approaches should be taken to avoid problems and exploit the opportunities offered by solid state properties in the pharmaceutical and agricultural industries. With its practical approach, this is at once a guideline for development chemists just entering the field as well as a high-quality source of reference material for specialists in the pharmaceutical and chemical industry, structural chemists, physicochemists, crystallographers, inorganic chemists, and patent departments.

After gaining his PhD in physical chemistry from Basel University, Switzerland, Rolf Hilfiker did his postdoc at Stony Brook, USA. He returned to Basel as a research fellow, initially at the university and then at Ciba-Geigy. In 1997 he became head of Stability & Kinetics group at Novartis, joining Solvias two years later where he is currently head of the department Solid-State Development. Dr. Hilfiker has taught physical chemistry in New York and Basel, and is a recipient of the Jacottet-K?ard and a Treubel Fellowship. He is author of more than 50 scientific publications in various areas of physical chemistry.

Relevance of Solid-state Properties for Pharmaceutical Products Thermodynamics of Polymorphs Characterization of Polymorphic Systems using Thermal Analysis Solid-state NMR Spectroscopy Vibrational Spectroscopic Methods in Pharmaceutical Solid-state Characterization Crystallography for Polymorphs Light Microscopy The Importance Solvates Physical Characterization of Hygroscopicity in Pharmaceutical Solids The Amorphous State Approaches to Polymorphism Screening Salt Selection Processing-induced Phase Transformations and their Implications on Pharmaceutical Product Quality Polymorphism and Patents from A Chemist's Point of View Scientific Considerations of Pharmaceutical Solid Polymorphism in Regulatory Applications

Verlagsort Weinheim
Sprache englisch
Gewicht 10 g
Themenwelt Naturwissenschaften Chemie
ISBN-10 3-527-60788-9 / 3527607889
ISBN-13 978-3-527-60788-4 / 9783527607884
Zustand Neuware
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