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Highlights in Bioorganic Chemistry – Methods and Applications

C Schmuck (Autor)

Software / Digital Media
600 Seiten
2005
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-60372-5 (ISBN)
214,95 inkl. MwSt
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Provides an introduction to the topic, spanning the spectrum of nucleic acid chemistry, carbohydrates, peptides, molecular recognition, biosynthesis and natural biosynthesis, and medical and biophysical chemistry. This book offers an account of the research in such areas as artificial receptors for the stabilization of beta sheet structures.
This is a fascinating introduction to the topic. Spanning the spectrum of nucleic acid chemistry, carbohydrates, peptides, molecular recognition, biosynthesis and natural biosynthesis, right up to medical and biophysical chemistry, the book provides advanced students and those already working in the field with a balanced overview. In more than 30 contributions, a new generation of recognized scientists gives an account of the latest research in such areas as: Artificial receptors for the stabilization of beta sheet structures; Carbohydrate recognition by artificial receptors; Combinatorial chemistry as a tool for the discovery of catalysts; The interaction of NO and peroxynitrite with hemoglobin and myoglobin; Inhibitors against human mast cell tryptase as a potential approach to conquering asthma; and, the selectivity of DNA replication. This work offers a readily accessible survey for everyone wishing to stay abreast of developments. It comes with a Foreword by Ronald Breslow.

Carsten Schmuck is Professor of Organic Chemistry at the University of Wurzburg. He studied chemistry and obtained his PhD at the Ruhr University in Bochum. After a postdoctorate at Columbia University in New York, he carried out his Habilitation at the University of Cologne and joined the Unviersity of Wurzburg as associate professor in 2002. Helma Wennemers is Professor of Organic Chemistry at the University of Basel. She studied chemistry at the Johann Wolfgand Goethe University in Frankfurt and obtained her PhD at the Columbia University in New York. After a postdoctorate at Nagoya University in Japan she joined the University of Basel as assistant professor and was promoted to associate professor in 2003.

STRUCTURE OF BIOMOLECULES b amino acids in Nature: Biosynthesis and Biology Artificial receptors for the stabilization of b sheet structures Conformational equilibria of RNA Conformational restriction of sphingolipids Stabilization of peptide microstructures by coordniation of metal ions Synthesis and application of proline and piccolic acid derivatives: tools for stabilization of peptide secondary structures. INTERMOLECULAR INTERACTIONS (BINDING) Artificial rotary motors at the molecular level Carbohydrate recognition by artificial receptors Synthetic approaches to study carbohydrate lectin interactions Cyclopeptides as macrocyclic host molecules for charged guests Combinatorial chemistry as a tool for the development of molecular receptors for small peptides The design of new binding motifs for c terminal peptides INTERACTION OF SMALL MOLECULES WITH BIOLOGICAL SYSTEMS (FUNCTION) Modulation of biochemical processes by synthetic hosts for substrates Interaction of NO and peroxynitrite with hemoglobin and myoglobin Oxidative splitting of pyrimidine cyclobutane dimers Inhibitors against human mast cell tryptase: a potential approach to attack asthma? Selectivity of DNA replication Acridizinium salts and their photophysical interaction with DNA DNA detection in homogeneous solution

Erscheint lt. Verlag 27.5.2005
Verlagsort Weinheim
Sprache englisch
Gewicht 10 g
Themenwelt Naturwissenschaften Biologie Biochemie
ISBN-10 3-527-60372-7 / 3527603727
ISBN-13 978-3-527-60372-5 / 9783527603725
Zustand Neuware
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