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Pharmacogenomics – The Search for Individualized Therapies

J Licinio (Autor)

Software / Digital Media
599 Seiten
2003
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-60075-5 (ISBN)
138,65 inkl. MwSt
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Providing coverage of pharmacogenomics, this work leads to the understanding of the key genetic differences between individuals and permits the individual tailoring of pharmacological treatments. It also contributes to the discovery of new targets for drug development.
This is the very first comprehensive coverage of pharmacogenomics a new discipline that will revolutionize health care. "Pharmacogenomics" leads to the understanding of the key genetic differences between individuals and will permit the individual tailoring of pharmacological treatments. Improved therapeutics can reach new levels by being able to differentiate between individuals according to their susceptibility to disease processes or adverse effects of medication. "Pharmacogenomics" also contributes to the discovery of new targets for drug development. Outstanding experts in the field present an overview of the latest work in this young and promising approach and provide an insight into the recent findings for all relevant disease classes. It is indispensable for a wide audience of experts working in the various areas that contribute to this field such as pharmacology, genetics, molecular biology, pharmaceutics, medicinal chemistry and clinical medicine.

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Introduction to Pharmacogenomics: Promises, Opportunities, and Limitations The Human Genome Turning SNPs into Useful Markers of Drug Response Association Studies in Pharmacogenomics Genomics Applications that Facilitate the Understanding of Drug Action and Toxicity The Role of Pharmacogenomics in Drug Discovery and Therapeutics Pharmacogenomics and Drug Design The Pharmacogenomics of Human P glycoprotein Pharmacogenomics of Drug Transporters Pharmacogenomics of Asthma Treatment Endothelial Cells are Targets for Hydroxy Urea: Relevance to the Current Therapeutic Strategy in Sickle Cell Disease Pharmacogenomics and Complex Cardiovascular Disease Clinical Studies in Candidate Genes Pharmacogenomics of Lipid lowering Agents Pharmacogenomics of Chemotherapeutic Agents in Cancer Treatment Pharmacogenomics of the Blood Brain Barrier Pharmacogenomics and the Treatment of Neurological Disease Pharmacogenomics of Neurodegenerative Diseases: Examples and Perspectives Psychiatric Pharmacogenomics: Prediction of Treatment Outcomes in Schizophrenia Pharmacogenomics of Major Depression and Antidepressant Treatment Pharmacogenomics of Bipolar Disorder Pharmacogenomics of Alcoholism Pharmacogenomics of Tobacco Addiction Pharmacogenomics of Opioid Systems Ethnicity and Pharmacogenomics Pharmacogenomics: Ensuring Equity Regarding Drugs Based on Genetic Difference Translation of Vascular Proteomics into Individualized Therapeutics Glossary of Key Terms in Molecu lar Genetics of Pharmacogeno mics Index

Erscheint lt. Verlag 12.5.2003
Verlagsort Weinheim
Sprache englisch
Gewicht 10 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete
Naturwissenschaften Biologie
ISBN-10 3-527-60075-2 / 3527600752
ISBN-13 978-3-527-60075-5 / 9783527600755
Zustand Neuware
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