Interaction of Cells with Natural and Foreign Surfaces

Section 1 Cell Surface Membranes: Molecular and Electrokinetic Properties.- Structural organisation and function of cell surface membranes.- Electrokinetic aspects of cell surfaces.- Fibronectin: Role in cell surface interactions.- Cytoskeletal and cytocontractile features of myofibroblasts.- Section 2 Cell Surface Interactions and Biotolerance: Basic Aspects.- Endothelium as a haemocompatible surface.- Interaction of blood, blood components and surfaces.- Cellular aspects of biotolerance.- Surface property requirements for biomaterials.- Surface emission and biological probes for inorganic interfaces.- Section 3 Cellular Interactions in Vascular Grafts and Extracorporeal Circuitry.- Cellular interactions in extracorporeal circuitry.- Interactions of white cells and the humoral cascades during cardiopulmonary bypass in man.- Assessment of platelet inhibitory therapy for arterial prostheses in an invivo canine model.- Evolution of the subendothelial growth on heparinised aldehyde crosslinked arteries.- The influence of thromboxane receptor blockade on platelet uptake in dacron grafts in man.- Plasma fibronectin and platelet deficiency following aortic cross-clamping.- Section 4 Cell Surface Interactions and Tumour Metastases.- Cell surface alterations and the metastatic behavior of tumor cells.- Interaction of platelets, tumor cells and subendothelial surfaces.- Fibrinolysis and its effect on tumour growth and metastasis.- Pericellular proteoglycans and metastasis formations Modulation by hydrocortisone and growth factors.- Section 5 Cellular Interactions: Granulomas, Healing Wounds, Dressings and Sutures.- The mononuclear phagocyte system in granulomas.- The role of collagen in healing wounds.- The rabbit ear chamber: A study of cell interactions.- The treatment of skin graft donor sites.- The effect of surgical dressings on skin temperature.- Cellular responses to sutures.- Section 6 Other Clinical Aspects of Biocompatibility.- An experimental study of calculogenesis and biocompatibility of plastics for urological use.- The mechanical and biological properties of filamentous carbon or polypropylene mesh in the rat abdominal wall.- The possible role of implant materials in promoting the aseptic loosening of prosthetic joints.- Evaluation of the histologic response to a polyacrylamide-agar hydrogel in the rat.- Cellular interactions with dental materials.- CELL-SURFACE INTERACTIONS Summary and Concluding Remarks.- Contributors.