Cell Polarity and Subcellular RNA Localization

Localization of mRNAs at Synaptic Sites on Dendrites.- 1 Introduction.- 2 The Machinery for Translation in Dendrites.- 3 Types of Proteins That Are Synthesized at SPRCs.- 4 Activity-Dependent Regulation of mRNA Trafficking in Dendrites.- 5 Signals That Mediate mRNA Routing and Localization.- 6 Conclusion.- References.- Long-Lasting Hippocampal Plasticity: Cellular Model for Memory Consolidation?.- 1 Introduction.- 2 How?.- 3 Where?.- 4 When?.- 5 Conclusion.- References.- Neuronal RNA Localization and the Cytoskeleton.- 1 Localization of Cytoskeletal Proteins to Neuronal Processes and Growth Cones.- 2 Regulation of Neuronal mRNA Localization.- 3 Mechanism of mRNA Localization.- 4 mRNA May Be Transported as Particles or Granules.- 5 Future Directions.- References.- Transcription Factors in Dendrites: Dendritic Imprinting of the Cellular Nucleus.- 1 Introduction.- 2 CREB mRNA Is Localized to Neuronal Dendrites.- 3 CREB Protein Is Present in Dendrites.- 4 CREB Protein Moves from the Dendrite to the Cell Nucleus.- 5 Potential Importance of Dendritic CREB in Modulating.- Neuronal Functioning.- 6 Biological Impetus tor Dendritic Imprinting.- References.- RNA Trafficking in Oligodendrocytes.- 1 Introduction.- 2 A2RE Is a cis-Acting RNA Trafficking Determinant.- 3 hnRNP A2 Is a trans-Acting RNA Trafficking Factor.- 4 A2RE/hnRNP A2-Mediated Nuclear Export.- 5 A2RE/hnRNP A2-Mediated Granule Assembly.- 6 A Dual Motor Mechanism for RNA Trafficking on Microtubules.- 7 RNA Trafficking in the Virtual Cell.- 8 The Taxol Paradox.- 9 Negotiating Branch Points.- 10 Translation Regulation.- 11 Summary.- References.- Extrasomatic Targeting of MAP2, Vasopressin and Oxytocin mRNA in Mammalian Neurons.- 1 Introduction.- 2 Microtubule-Associated Protein 2.- 3 Axonal and Dendritic Targeting of VPand OT mRNAs.- 4 Final Conclusions and Perspectives.- References.- RNA Transport and Local Protein Synthesis in the Dendritic Compartment.- 1 Introduction.- 2 Differential Subcellular RNA Localization in Neurons.- 3 RNA Transport.- 4 Synapse and Local Protein Synthesis Machinery.- 5 Activity-Dependent mRNA Transport and Protein Synthesis.- 6 Conclusions and Perspectives.- References.- Neuronal BC1 RNA: Intracellular Transport and Activity-Dependent Modulation.- 1 Evolutionary Relationships.- 2 Intracellular Transport.- 3 Activity-Dependent Regulation.- 4 Outlook.- References.- Nucleocytoplasmic mRNA Transport.- 1 Introduction.- 2 The Export Machinery.- 4 Conclusions.- References.- RNA Localization in Xenopus Oocytes.- 1 Introduction.- 2 The Early Localization Pathway.- 3 The Late Pathway.- 4 The Animal Localization Pathway.- 5 Concluding Remarks.- References.- Local Protein Synthesis in Invertebrate Axons: From Dogma to Dilemma.- 1 Introduction.- 2 mRNA in Axons.- 3 Translocation of mRNA.- 4 Origin of RNA.- 5 Protein Synthesis in Axons.- 6 The Identity of Protein Synthetic Machinery in Axons.- 7 Which Proteins Are Synthesized in Axons?.- 8 Functions of Local Protein Synthesis.- 9 Discussion.- References.- Nucleocytoplasmic RNA Transport in Retroviral Replication.- 1 Introduction.- 2 Retroviral Replication.- 3 RNA Export in Simple versus Complex Retroviruses.- 4 Regulation of HIV-1 Gene Expression: An Overview.- 5 CTE: The Constitutive RNA Transport Elements of D-Type Retroviruses.- 6 Summary and Conclusions.- References.