Cancer -

Cancer

Rob Bradbury (Herausgeber)

Buch | Softcover
XIV, 452 Seiten
2010 | 1. Softcover reprint of hardcover 1st ed. 2007
Springer Berlin (Verlag)
978-3-642-06966-6 (ISBN)
213,99 inkl. MwSt
With contributions by numerous experts
lt;p>This volume reviews advances in cancer chemotherapy research over the last 10 years. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs. Each chapter covers the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.

Overview.- Anti-hormone Therapy: Principles of Endocrine Therapy of Cancer.- Inhibition of Growth Factor Signaling by Small-Molecule Inhibitors of ErbB, Raf, and MEK.- Farnesyl Protein Transferase Inhibitors: Medicinal Chemistry, Molecular Mechanisms, and Progress in the Clinic.- Survival Signaling.- Progress in the Development of Agents to Control the Cell Cycle.- HDAC Inhibition in Cancer Therapy: An Increasingly Intriguing Tale of Chemistry, Biology and Clinical Benefit.- Development of Angiogenesis Inhibitors to Vascular Endothelial Growth Factor Receptor 2 for Cancer Therapy.- Novel Small-Molecule Inhibitors of Src Kinase for Cancer Therapy.- Bcr-Abl Kinase Inhibitors.

Erscheint lt. Verlag 19.11.2010
Reihe/Serie Topics in Medicinal Chemistry
Zusatzinfo XIV, 452 p. 32 illus., 4 illus. in color.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 702 g
Themenwelt Medizin / Pharmazie Pharmazie
Medizin / Pharmazie Studium
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Chemie Physikalische Chemie
Schlagworte angiogenesis • Biology • Cancer • Chemistry • Chemotherapy • medicinal chemistry • Tumorigenesis • tumour
ISBN-10 3-642-06966-5 / 3642069665
ISBN-13 978-3-642-06966-6 / 9783642069666
Zustand Neuware
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