From Genome to Proteome – Advances in the Practice and Application of Proteomics
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-61348-9 (ISBN)
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As research on the human, animal, plant and microbial genomes matures towards descriptive fullness, the need for understanding the proteome has clearly emerged as the next major endeavor of life sciences. Proteomics - the quantitative analysis of all proteins working in a cell at a specific time and at specific conditions - provides deep insight into the highly organized network of expression, modification and degradation of proteins. Compiled in this book are reviews and research articles which describe the recent advances and perspectives of this new field of research.The articles are grouped into the following sections: Sample Preparation and Solubilization, Developments in Electrophoresis, Detection and Quantitation, Mass Spectrometry, Proteome Data Analysis and Management, Prokayotes and Yeast, Biological Fluids, Eukaryotic Cells and Tissue, and Oncology. Plants Proteomics is a new key for the functional analysis of living systems and of equal importance for basic as well as application oriented research.
Michael J. Dunn is Professor of Biomedical Proteomics at University College, Dublin, where he is doing proteomics research in the areas of cardiovascular disease, transplantation and neurological disease. He was previously Professor of Proteomics at the Institute of Psychiatry, King's College London. Dr. Dunn is the current President of the British Society for Proteome Research and the Editor-in-Chief of the journal Proteomics. He is also a founder Council Member of the Human Proteome Organisation and a member of the Executive Committee of the HUPO Brain Proteome Project.
REVIEWS Proteome analysis: A pathway to the functional analysis of proteins Proteomics in human disease: Cancer, heart and infectious disease Proteomics for genetic and physiological studies in plants Diagnosis of cellular states of microbial organisms using proteomics Candida albicans pathogenicity: A proteomic perspective Genotypes and phenotypes Replication-induced protein synthesis and its importance to proteomics Advances in protein solubilization for two-dimensionional electrophoresis Proteomics and automation Genomes and proteomes: Towards a multidimensional view of biology RESEARCH ARTICLES GROUPED INTO SECTIONS Sample preparation and solubilization Developments in electrophoresis Detection and quantitation Mass spectrometry Proteome data analysis and management Prokaryotes and yeast Biological fluids Eukaryotic cells and tissue Oncology Plants
| Verlagsort | Weinheim |
|---|---|
| Sprache | englisch |
| Maße | 172 x 246 mm |
| Gewicht | 1160 g |
| Themenwelt | Naturwissenschaften ► Biologie |
| Naturwissenschaften ► Chemie | |
| ISBN-10 | 3-527-61348-X / 352761348X |
| ISBN-13 | 978-3-527-61348-9 / 9783527613489 |
| Zustand | Neuware |
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