RNA Technologies in Cardiovascular Medicine and Research -

RNA Technologies in Cardiovascular Medicine and Research

Buch | Softcover
XIV, 358 Seiten
2010 | 1. Softcover reprint of hardcover 1st ed. 2008
Springer Berlin (Verlag)
978-3-642-09746-1 (ISBN)
235,39 inkl. MwSt
In this urgently needed book the authors review the field and explore the potential role of RNAi and other RNA technologies in cardiovascular medicine and research. They highlight the impressive recent progress but also the hurdles that must still be overcome.

In this book the authors review the field and explore the potential role of RNAi and other RNA technologies in cardiovascular medicine and research. They highlight the impressive recent progress but also the hurdles that still must be overcome before this promising technology is finally ready for translation and clinical use.

MicroRNA.- An Overview of MicroRNA.- MicroRNAs and Their Potential.- miRNAs and Their Emerging Role in Cardiac Hypertrophy.- MicroRNAs and the Control of Heart Pathophysiology.- MicroRNA Systems Biology.- RNA Interference.- Targeting Viral Heart Disease by RNA Interference.- Design of siRNAs and shRNAs for RNA Interference: Possible Clinical Applications.- RNA Interference and MicroRNA Modulation for the Treatment of Cardiac Disorders.- Cardiac Delivery of Nucleic Acids by Transcriptional and Transductional Targeting of Adeno-Associated Viral Vectors.- Ribozymes.- Characterization of Hammerhead Ribozymes Potentially Suitable for the Treatment of Hyper-Proliferative Vascular Diseases.- Applications of Ribozymes and Pyrrole-Imidazole Polyamides for Cardiovascular and Renal Diseases.- Noncoding, Aptamer and Antisense RNAs.- Noncoding RNAs in Human Diseases.- Aptamers and siRNAs in Cardiovascular Disease.- Nucleic Acid Aptamers for Cardiovascular Therapeutics.- NF?B Decoy Oligodeoxynucleotide-Based Therapy in Cardiovascular Diseases.- Antisense Therapy for Restenosis Following Percutaneous Coronary Interventions.- Toxic RNA in Pathogenesis of Human Neuromuscular Disorders.

Erscheint lt. Verlag 19.10.2010
Zusatzinfo XIV, 358 p. 55 illus.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 559 g
Themenwelt Studium 2. Studienabschnitt (Klinik) Humangenetik
Naturwissenschaften Biologie Biochemie
Schlagworte Biology • Cardiovascular • Cardiovascular Research • heart • microRNA • miRNAs • Nucleic acid • Nucleotide • Ribozyme • RNA • transcription • Translation • vascular disease
ISBN-10 3-642-09746-4 / 3642097464
ISBN-13 978-3-642-09746-1 / 9783642097461
Zustand Neuware
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