Cytochromes P450

Examines cytochromes P450 proteins and their role in toxicity/carcinogenicity and the metabolism of foreign chemicals. The text, a study of the function of these proteins, presents methods for predicting the pathways and outcome of chemical metabolism.

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Cytochromes P450: Metabolic and Toxicological Aspects examines cytochrome P450 proteins and their role in toxicity/carcinogenicity and the metabolism of foreign chemicals. Studying the function of these proteins enables us to:
Predict the pathways and outcome of chemical metabolism to rationalize species, sex, and age differences in toxicity

Anticipate drug interactions

Modify doses to fit the needs of patients
Contributions from internationally acknowledged experts are organized into three sections. The first section provides an overview, the next profiles each of the cytochrome P450 families and subfamilies involved in chemical metabolism, and the last section discusses new issues and developments of current interest.
This detailed and thorough examination of cytochrome P450 will be a useful source for research scientists, especially those working in the pharmaceutical industry, dealing with the safety evaluation of chemicals and the study of their metabolism, pharmacokinetics, and toxicological properties.