Cryptococcus

From Human Pathogen to Model Yeast

Joseph Heitman, Thomas R Kozel, Kyung J Kwon-Chung, John R Perfect (Autoren)

Buch | Hardcover

646 Seiten

2010
American Society for Microbiology (Verlag)
978-1-55581-501-1 (ISBN)

Artikel merken

Provides an up-to-date review of problems posed by medically important fungi Covers the most important medically important fungi, the molecular manipulation and analysis of these fungi, host-fungal interactions, basic concepts of pathogenesis as they apply to mycoses, and molecular methods applied to analyses of fungal diseases.

The full range of scientific and clinical perspectives on Cryptococcus at your fingertips.

Covers both the Cryptococcus neoformans and Cryptococcus gattii species, examining in detail the life cycle, pathophysiology, molecular biology, genetics, genomics, epidemiology, immunology, and clinical management of this encapsulated yeast.
Provides in-depth discussions of the 1999 Vancouver Island C. gattii outbreak that spread to the Canadian mainland and the United States, causing infections in both humans and animals.
Discusses diagnosis, treatment, prevention, and other clinical perspectives on Cryptococcus infection
Serves as a resource for molecular biologists, microbiologists, public health officials, epidemiologists, and infectious disease clinicians.

This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.

Table of Contents

I. GENERAL PRINCIPLES

1. Systematics of the Genus Cryptococcus and Its Type Species C. neoformans, Kyung J. Kwon-Chung, Teun Boekhout, Brian L. Wickes, and Jack W. Fell

2. The History of Cryptococcus and Cryptococcosis, John R. Perfect and Arturo Casadevall

3. Biosynthesis and Genetics of the Cryptococcus Capsule, Guilhem Janbon and Tamara L. Doering

4. The Architecture and Antigenic Composition of the Polysaccharide Capsule, Marcio L. Rodrigues, Arturo Casadevall, and Oscar Zaragoza

5. Melanin: Structure, Function, and Biosynthesis in Cryptococcus, David Trofa, Arturo Casadevall, and Joshua D. Nosanchuk

6. The Cell Wall of Cryptococcus, Nicole M. Gilbert, Jennifer K. Lodge, and Charles A. Specht

7. Sexual Reproduction of Cryptococcus, Yen-Ping Hsueh, Xiaorong Lin, Kyung J. Kwon-Chung, and Joseph Heitman

8. Population Structure and Ecology of Cryptococcus neoformans and C. gattii, Anastasia P. Litvintseva, Jianping Xu, and Thomas G. Mitchell

II. GENETICS AND GENOMICS

9. The Cryptococcus Genomes: Tools for Comparative Genomics and Expression Analysis, James W. Kronstad, Brendan J. Loftus, and Jennifer K. Lodge

10. Genetic and Genomic Approaches to Cryptococcus Environmental and Host Responses, Alexander Idnurm and Peter R. Williamson

11. The Mating Type Locus of Cryptococcus: Evolution of Gene Clusters Governing Sex Determination and Sexual Reproduction, from the Phylogenomic Perspective, Yen-Ping Hsueh, Banu Metin, Keisha Findley, Marianela Rodriguez-Carres, and Joseph Heitman

III. SIGNALING AND VIRULENCE

12. G-Protein Signaling Pathways Regulating Morphogenesis and Virulence of Cryptococcus, J. Andrew Alspaugh, Connie B. Nichols, Chaoyang Xue, Wei-Chiang Shen, and Ping Wang

13. A Role for Mating in Cryptococcal Virulence, Kirsten Nielsen and Kyung J. Kwon-Chung

14. Sensing Extracellular Signals in Cryptococcus neoformans, Alexander Idnurm, Yong-Sun Bahn, Wei-Chiang Shen, Julian C. Rutherford, and Fritz A. Muhlschlegel

15. Virulence Mechanisms of Cryptococcus gattii: Convergence and Divergence, Sudha Chaturvedi and Vishnu Chaturvedi

16. Drug Resistance in Cryptococcus: Epidemiology and Molecular Mechanisms, Michael A. Pfaller, Jennifer K. Lodge, and M. A. Ghannoum

17. Signaling Cascades and Enzymes as Cryptococcus Virulence Factors, Deborah S. Fox, Julianne Djordjevic, and Tania C. Sorrell

IV. ENVIRONMENTAL INTERACTIONS AND POPULATION GENETICS

18. Environmental Niches for Cryptococcus, Thomas G. Mitchell, Elizabeth Castaneda, Kirsten Nielsen, Bodo Wanke, and Marcia S. Lazera

19. Cryptococcus neoformans: Nonvertebrate Hosts and the Emergence of Virulence, Jeffrey J. Coleman, Cara J. Chrisman, Arturo Casadevall, and Eleftherios Mylonakis

20. Cryptococcosis in Africa, Nelesh Govender, Thomas G. Mitchell, Anastasia P. Litvintseva, and Kathleen J. Miglia

21. Cryptococcosis in Asia, Jiangping Xu, Weerawat Manosuthi, Uma Banerjee, Li-Ping Zhu, Janghan Chen, Shigeru Kohno, Koichi Izumikawa, Yuchong Chen, Somnuek Sungkanuparph, Thomas S. Harrison, and Matthew Fisher

22. Sexual Reproduction of Cryptococcus gattii: a Population Genetics Perspective, Dee Carter, Leona Campbell, Nathan Saul, and Mark Krockenberger

23. The Emergence of Cryptococcus gattii Infections on Vancouver Island and Expansion in the Pacific Northwest, Karen Bartlett, Edmond Byrnes, Colleen Duncan, Murray Fyfe, Eleni Galanis, Joseph Heitman, Linda Hoang, Sarah Kidd, Laura MacDougall, Sunny Mak, Kieren Marr, Muhammad Morshed, Sarah Klizas West, and James Kronstad

24. Molecular Typing of the Cryptococcus neoformans/C. gattii Species Complex, Wieland Meyer, Felix Gilgado, Popchai Ngamskulrungroj, Luciana Trilles, Ferry Hagen, Elizabeth Castaneda, and Teun Boekhout

25. Hybridization and Its Importance in the Cryptococcus Species Complex, Massimo Cogliati, Xiaorong Lin, and Maria Anna Viviani

V. INTERACTIONS WITH THE IMMUNE SYSTEM

26. The Interaction of Cryptococcus neoformans with Host Macrophages and Neutrophils, Travis McQuiston and Maurizio Del Poeta

27. T-Cell and Dendritic-Cell Immune Responses to Cryptococcus, Karen L. Wozniak and Stuart M. Levitz

28. Acquired Humoral Immunity to Cryptococcus neoformans, Liise-anne Pirofski and Arturo Casadevall

29. Interactions of Capsule with Antibody and Complement, Thomas R. Kozel

30. Cryptococcus Interactions with Innate Cytotoxic Lymphocytes, Shaunna M. Huston and Christopher H. Mody

VI. PATHOGENESIS OF CRYPTOCOCCUS

31. Cryptococcus neoformans: Latency and Disease, Francoise Dromer, Arturo Casadevall, John Perfect, and Tania Sorrell

32. Intracellular Replication and Exit Strategies, Kerstin Voelz, Simon A. Johnston, and Robin C. May

33. Pulmonary Innate and Adaptive Defenses against Cryptococcus, Kristi L. Williams, Floyd L. Wormley, Jr., Scarlett Geunes-Boyer, Jo Rae Wright, and Gary B. Huffnagle

34. Invasion of Cryptococcus into the Central Nervous System, Francoise Dromer and Stuart M. Levitz

35. Cryptococcosis in Experimental Animals: Lessons Learned, Karl V. Clemons and David A. Stevens

36. Veterinary Insights into Cryptococcosis Caused by Cryptococcus neoformans and Cryptococcus gattii, Richard Malik, Mark B. Krockenberger, Carolyn R. O'Brien, Dee A. Carter, and Wieland Meyer

VII. DIAGNOSIS, TREATMENT, PREVENTION, AND CLINICAL PERSPECTIVES

37. Cryptococcosis in Transplant Recipients, Nina Singh and Barbara D. Alexander

38. Cryptococcosis in AIDS, Bettina C. Fries and Gary M. Cox

39. Antifungal Trials: Progress, Approaches, New Targets, and Perspectives in Cryptococcosis, Peter G. Pappas

40. Vaccines and Antibody Therapies from Cryptococcus neoformans to Melanoma, Arturo Casadevall, Ekaterina Dadachova, and Liise-anne Pirofski

41. Diagnostic Approach Based on Capsular Antigen, Capsule Detection, ss-Glucan, and DNA, Mara R. Diaz and M. Hong Nguyen

42. Management of Cryptococcal Meningoencephalitis in Both Developed and Developing Countries, Joseph N. Jarvis, Tihana Bicanic, and Thomas S. Harrison

43. Public Health Importance of Cryptococcal Disease: Epidemiology, Burden, and Control, Benjamin J. Park, Shawn R. Lockhart, Mary E. Brandt, and Tom M. Chiller

44. Clinical Perspectives on Cryptococcus neoformans and Cryptococcus gattii: Implications for Diagnosis and Management, Tania C. Sorrell, Sharon C.-A. Chen, Peter Phillips, and Kieren A. Marr

Verlagsort	Washington DC
Sprache	englisch
Gewicht	1850 g
Einbandart	gebunden
Themenwelt	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Themenwelt	Naturwissenschaften ► Biologie ► Mykologie
ISBN-10	1-55581-501-4 / 1555815014
ISBN-13	978-1-55581-501-1 / 9781555815011
Zustand	Neuware