Clusterin, Part B -

Clusterin, Part B

Buch | Hardcover
350 Seiten
2009
Academic Press Inc (Verlag)
978-0-12-381429-6 (ISBN)
155,85 inkl. MwSt
Contains information on the field of cancer research. This title provides an overview and synthesis of the thoughts and findings relating to Clusterin. It includes the chapters such as CLU Gene expression, CLU and prostate cancer, CLU and breast cancer, and CLU and prostate cancer.
The biological function of clusterin (CLU, also known as ApoJ, SGP2, TRPM2, CLI) has been puzzling researchers since its discovery and characterization in the early 1980s. Approaches such as cloning, expression and functional characterization of the different protein products generated by the CLU gene have now produced a critical mass of information of tremendous biological importance that are teaching us an important lesson in molecular biology of gene expression regulation. This volume brings together the contributions of top researchers in the field, providing an overview and synthesis of the latest thought and findings relating to CLU.

1.    CLU and prostate cancer.

S. Bettuzzi and F. Rizzi

2.    The role of Clusterin (CLU) in malignant transformation and drug resistance in breast carcinomas

Maximino Redondo; Teresa Tellez; María Jose Roldan.

3.    CLU and COLON CANCER

The dual face of CLU: from normal to malignant phenotype

Mazzarelli P. Pucci S. Spagnoli L.G.

4.    Clusterin (CLU) and lung cancer

F. Panico*, 2F. Rizzi*, 1L.M. Fabbri, and 2S. Bettuzzi°, 1F. Luppi°

5.    CLUSTERIN AND CHEMORESISTANCE

Julie Y. Djeu and Sheng Wei

6.    CLU "in and out": looking for a link

Pucci S.1 , Mazzarelli P. 1 , Nucci C. 2, Ricci F. 2, Spagnoli L.G. 1

7. Regulation of CLU gene expression by oncogenes and epigenetic factors: Implications for tumorigenesis

Arturo Sala, 2 * Saverio Bettuzzi, 3 Sabina Pucci, 1 Olesya Chayka, 4 Michael Dews, and 4 Andrei Thomas-Tikhonenko

8. CONCLUSIONS AND PERSPECTIVES

Saverio Bettuzzi

Reihe/Serie Advances in Cancer Research
Verlagsort San Diego
Sprache englisch
Maße 152 x 229 mm
Gewicht 470 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Naturwissenschaften Biologie Genetik / Molekularbiologie
ISBN-10 0-12-381429-4 / 0123814294
ISBN-13 978-0-12-381429-6 / 9780123814296
Zustand Neuware
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