The DNA Damage Response: Implications on Cancer Formation and Treatment
DNA Damage Sensing and Signaling.- Signaling at Stalled Replication Forks.- An Oncogene-Induced DNA Replication Stress Model for Cancer Development.- Cellular Responses to Oxidative Stress.- Cell Cycle Regulation and DNA Damage.- Chromatin Modifications Involved in the DNA Damage Response to Double Strand Breaks.- Telomere Metabolism and DNA Damage Response.- DNA Double Strand Break Repair: Mechanisms and Therapeutic Potential.- DNA Base Excision Repair: A Recipe for Survival.- DNA Damage Tolerance and Translesion Synthesis.- Nucleotide Excision Repair: from DNA Damage Processing to Human Disease.- Chromosomal Single-Strand Break Repair.- Mouse Models of DNA Double Strand Break Repair Deficiency and Cancer.- Cancer Biomarkers Associated with Damage Response Genes.- Linking Human RecQ Helicases to DNA Damage Response and Aging.- Single-Stranded DNA Binding Proteins Involved in Genome Maintenance.- The Fanconi anemia-BRCA Pathway and Cancer.- BRCA1 and BRCA2: Role in the DNA Damage Response, Cancer Formation and Treatment.
Erscheint lt. Verlag | 18.11.2009 |
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Zusatzinfo | XII, 449 p. |
Verlagsort | Dordrecht |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
Naturwissenschaften ► Biologie ► Humanbiologie | |
Naturwissenschaften ► Biologie ► Zoologie | |
ISBN-10 | 90-481-2560-X / 904812560X |
ISBN-13 | 978-90-481-2560-9 / 9789048125609 |
Zustand | Neuware |
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