Breast Cancer in the Post-Genomic Era

Buch | Hardcover
230 Seiten
2009 | 2009 ed.
Humana Press Inc. (Verlag)
978-1-60327-944-4 (ISBN)

Lese- und Medienproben

Breast Cancer in the Post-Genomic Era -
160,49 inkl. MwSt
Breast cancer is the most common tumor in women. It is the second leading cause of cancer deaths worldwide. In this book, international authorities offer a comprehensive approach to the biology, diagnosis, prevention, and treatment of human breast carcinoma.
Breast Cancer is the most common tumor in women and the second leading cause of cancer deaths worldwide. Due to breakthroughs in gene profiling, the knowledge of the pathophysiology of the mammary gland had greatly increased over the last decade. In Breast Cancer in the Post Genomic Era, Antonio Giordano, Nicola Normanno, and a panel of international authorities in their field provide a comprehensive approach to the biology, diagnosis, prevention, and treatment of human breast carcinoma.


The book provides a comprehensive approach to breast cancer, describing the use of gene profiling techniques to distinguish specific features of individual carcinomas, as well as emerging novel therapeutic approaches to treatment. Additional chapters cover the use of transgenic mice to model human breast cancer and the role of the EGF-CFC family in mammary gland development and neoplasia. Breast Cancer in the Post Genomic-Era succeeds in looking at breast cancer pathogenesis, diagnosis, and treatment under a more comprehensive light, and is a valuable resource for any Radiation or Surgical Oncologist, Cancer Biologist or Pathologist.

The Genomic Basis of Breast Development and Differentiation.- Mammary Glands, Stem Cells and Breast Cancer.- The Genetics of Breast Cancer.- Alterations in Cell Cycle Regulatory Genes in Breast Cancer.- Neuregulins in the Nucleus.- Role of the EGF-CFC Family in Mammary Gland Development and Neoplasia.- Modeling Human Breast Cancer.- Gene Expression Profiling in Breast Cancer.- TGF-? Signaling.- DNA Methylation in Breast Cancer.- Signal Transduction Inhibitors in the Treatment of Breast Cancer.- Integration of Target-Based Agents in Current Protocols of Breast Cancer Therapy.

Reihe/Serie Current Clinical Oncology
Zusatzinfo 10 Illustrations, color; 3 Illustrations, black and white; XI, 230 p. 13 illus., 10 illus. in color.
Verlagsort Totowa, NJ
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Chirurgie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium 2. Studienabschnitt (Klinik) Pathologie
Schlagworte Brustkrebs
ISBN-10 1-60327-944-X / 160327944X
ISBN-13 978-1-60327-944-4 / 9781603279444
Zustand Neuware
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