Statistical and Methodological Aspects of Oral Health Research

Emmanuel Lesaffre, Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Catholic University Leuven, Belgium. and University Hasselt, Belgium; Department of Biostatistics, Erasmus MC, Rotterdam, the Netherlands Jocelyne Feine, Oral Health and Society Research Unit, Faculty of Dentistry, McGill University, Quebec, Canada. Brian Leroux,Departments of Biostatistics and of Dental Public Health Sciences, University of Washington, Seattle, USA. Dominique Declerck, School for Dentistry, Catholic University Leuven, Belgium.

List of Contributors. Preface.

Part I.

1 Do We Need to Improve Oral Health Research? (Dominique Declerck and Emmanuel Lesaffre).

2 Grading Evidence with a Focus on Etiology, Surrogates, and Clinical Devices (Philippe Hujoel).

3 The Effective use of Research Data for Evidence-Based Oral Health Care (Ian Needleman and Helen Worthington).

Part II.

4 Planning a Research Project (Timothy A. DeRouen and Donald E. Mercante).

5 How to Carry out Successful Clinical Studies: Lessons from Project Management (Jocelyne S. Feine, Stephanie D. Wollin and Faahim Rashid).

6 Design and Analysis of Randomized Clinical Trials in Oral Health (Brian Leroux and Emmanuel Lesaffre).

7 Epidemiological Oral Health Studies: Aspects of Design and Analysis (Jimmy Steele and Mark Pearce).

8 Qualitative Research (Christophe Bedos, Pierre Pluye, Christine Loignon and Alissa Levine).

9 Data Validity and Quality (Finbarr Allen and Jimmy Steele).

Part III.

10 Start with the Basics (Manal A. Awad, Nico Nagelkerke and Emmanuel Lesaffre).

11 Statistical Methods for Studying Associations Between Variables (Brian G. Leroux).

12 Assessing Accuracy of Oral Health Diagnostic Tests (Todd A. Alonzo and Peter J. Giannini).

Part IV.

13 Analysis of Correlated Responses (Melissa D. Begg).

14 Missing Data and Informative Cluster Sizes (Stuart A. Gansky and John M. Neuhaus).

15 Failure Time Analysis (Thomas A. Gerds, Vibeke Qvist, J¨org R. Strub, Christian B. Pipper, Thomas H. Scheike and Niels Keiding).

16 Misclassification and Measurement Error in Oral Health (Helmut K¨uchenhoff).

17 Statistical Genetics (Amy D. Anderson).

18 The Bayesian Approach (Emmanuel Lesaffre, Arnoˇst Kom´arek and Alejandro Jara).

Part V.

19 Examples from Oral Health Epidemiology: The Signal Tandmobiel and Smile for Life studies (Dominique Declerck, Emmanuel Lesaffre, Roos Leroy and Jackie Vanobbergen).

20 Subantimicrobial-dose Doxycycline Effects on Alveolar Bone Loss in Postmenopausal Women: Example of a Randomized Controlled Clinical Trial (Julie A. Stoner and Jeffrey B. Payne).

Index.