Handbook of Epilepsy Treatment

Dr Simon Shorvon, University College London, Department of Clinical Neurology, London

Preface. Acknowledgements. 1: The clinical forms and causes of epilepsy. Epilepsy. The ILEA classification of seizure type. ILEA classification of the epilepsies and epilepsy. syndromes. Classification on partial seizures by anatomical site of. seizure onset. The age-related epilepsy syndromes. The causes of epilepsy. Epilepsy due to genetic or developmental causes. Epilepsy due to an acquired causes. Seizure precipitants. The reflex epilepsies. Acute symptomatic seizures. 2: The principles of drug treatment. Why treat epilepsy?. Pharmacokinetic principles of antiepileptic drug. treatment. Choice of drugs for different seizure types. Treatment of specific epilepsy syndromes. Principles of treatment of newly diagnosed patients. Principles of treatment of patients with established active. epilepsy. Treatment of patients with epilepsy in remission. Treatment of epilepsy in children. The treatment of epilepsy in the elderly. The treatment of epilepsy in women. The treatment of psychiatric disorders in epilepsy. Complementary and alternative therapy in epilepsy. Genetic counselling in epilepsy. 3: The antiepileptic drugs. Carbamazepine. Clobazam. Clonazepam. Ethosuximide. Gabapentin. Lamotrigine. Levetiracetam. Oxcarbazepine. Phenobarbital. Phenytoin. Pregabalin. Primidone. Tiagabine. Topiramate. Valproate. Vigabatrin. Zonisamide. Other drugs used in the treatment of epilepsy. Acetazolamide. Benzodiazepines. Diazepam. Clorazepate. Nitrazepam. Corticosteroids and adrenocorticotropic hormone. (ACTH). Felbamate. Mesuximide. Piracetam. Rufinamide. 4: The emergency treatment of epilepsy. The immediate management of a seizure. Status epilepticus. Antiepileptic drugs used in status epilepticus. 5: The surgical treatment of epilepsy. Introduction. Pre-surgical assessmentageneral points. Surgery in epilepsy arising in the mesial temporal lobe. Surgery in epilepsy arising in extra-temporal regions and in. the temporal neocortex. Surgery where no lesion is apparent on neuroimaging. Hemispherectomy, hemispherotomy and other large. resections. Corpus callosectomy (corpus callosum section, corpus. callosotomy. Multiple subpial transection. Vagus nerve stimulation. Other functional surgical procedures. The organization of epilepsy surgery care: the epilepsy. surgery centre. Pharmacopoeia