Pulmonary Hypertension

Marc Humbert, Joseph P. Lynch III

1. Classification and Epidemiology of Pulmonary Hypertension. 2. Pathology of Pulmonary Hypertension. 3. Pathogenesis of Pulmonary Arterial Hypertension (PAH). 4. Animal Models of Pulmonary Hypertension. 5. Genetics of PAH. 6. Imaging of Pulmonary Hypertension. 7. Echocardiography of PAH. 8. Diagnosis and Hemodynamic Assessment of PAH. 9. Idiopathic PAH. 10. PAH Complicating Connective Tissue Diseases. 11. PAH in Congenital Heart Diseases. 12. PAH and HIV Infection. 13. Portopulmonary Hypertension. 14. Pulmonary Hypertension Complicating Schistosomiasis. 15. Hemolysis-Associated Pulmonary Hypertension. 16. Pulmonary Veno-Occlusive Disease and Pulmonary Capillary Hemangiomatosis. 17. Pulmonary Hypertension in Obstructive Lung Diseases. 18. Pulmonary Hypertension in Restrictive Lung Diseases. 19. Chronic Mountain Sickness. 20. Chronic Thromboembolic Pulmonary Hypertension. 21. Medical Treatment of PAH: Basic Therapy and Calcium Channel Blockers. 22. Medical Treatment of PAH: Prostacyclins. 23. Medical Treatment of PAH: Phosphodiesterase Inhibitors. 24. Medical Treatment of PAH: Endothelin Receptor Antagonists. 25. Medical Treatment of PAH: Combination Therapy, Novel Agents, Future Directions and Current Recommendations. 26. Atrioseptostomy in PAH. 27. Surgical Management of PAH. 28. Lung Transplantation for Pulmonary Hypertension: Who Is a Candidate and When to List? 29. Pregnancy and PAH. 30. Management of PAH in the ICU. 31. End Points and Clinical Trial Designs in PAH: Clinical and Regulatory Perspectives.