Acquired Long QT Syndrome

A. John Camm, MD, FRCP, FESC, FACC Professor of Clinical Cardiology and Head, Department of Cardiological Sciences, St. George's Hospital Medical School, London Marek Malik, PhD, MD, DSc, FACC, FECS Professor of Cardiac Electrophysiology, Department of Cardiological Sciences, St. George's Hospital Medical School, London Yee Guan Yap, BMedSci, MBBS, MRCP British Heart Foundation Research Fellow in Cardiology, Department of Cardiological Sciences, St. George's Hospital Medical School, London

Chapter 1. Introduction. Chapter 2. Mechanisms of Acquired QT Prolongation and Torsades de Pointes. Chapter 3. Measurement of QT Interval and Repolarization Assessment. Chapter 4: Introduction to Drug-Induced Long QT Syndrome. Chapter 5: Risk of QT Prolongation and Torsades de Pointes with Antiarrhythmic Drugs. Chapter 6: Risk of QT Prolongation and Torsades de Pointes with Antihistamines. Chapter 7: Risk of QT Prolongation and Torsades de Pointes with Psychotrophic Drugs. Chapter 8: Risk of QT Prolongation and Torsades de Pointes with Antimicrobial and Antimalarial Drugs. Chapter 9: Risk of QT Prolongation and Torsades de Pointes with Prokinetics and Miscellaneous. Chapter 10: Acquired Long QT Syndrome Secondary to Cardiac Conditions. Chapter 11: Acquired Long QT Syndrome Secondary to Noncardiac Conditions. Chapter 12: Preclinical and Clinical Assessment of the Risk of QT Prolongation and Torsades de Pointes with New Active Substances. Chapter 13: Conclusion and Perspective of Drug-Induced Repolarization Changes