Applied Clinical Pharmacokinetics

Larry A. Bauer, Pharm.D. is a Professor at the University of Washington School of Pharmacy and has been on the faculty since 1980. He also holds an adjunct appointment at the same rank in the Department of Laboratory Medicine where he is a toxicology consultant. He received his Bachelor of Science in Pharmacy degree (1977) from the University of Washington, and his Doctor of Pharmacy degree (1980) from the University of Kentucky. He also completed an ASHP-accredited hospital pharmacy residency (1980) specializing in clinical pharmacokinetics from A. B. Chandler Medical Center at the University of Kentucky under the preceptorship of Dr. Paul Parker. Dr. Bauer is a fellow of the American College of Clinical Pharmacology and the American College of Clinical Pharmacy. Dr. Bauer's specialty area is in clinical pharmacokinetics, and he teaches courses and offers clinical clerkships in this area. He is the author of Applied Clinical Pharamcokinetics (McGraw-Hill, 2001) His research interests include the pharmacokinetics and pharmacodynamics of drug interactions, the effects of liver disease and age on drug metabolism, and computer modeling of population pharmacokinetics. Dr. Bauer is a member of several clinical pharmacology and clinical pharmacy professional organizations. He is a reviewer for several scientific publications, was Consulting Editor of Clinical Pharmacy (1981 - 1990) and Field Editor of ASHP Signal (1981 - 1983), and is currently on the Editorial Boards of Clinical Pharmacology and Therapeutics and Antimicrobial Agents and Chemotherapy. Dr. Bauer has precepted post-doctoral fellows in clinical pharmacokinetics and pharmacodynamics who currently have faculty appointments in schools of pharmacy or are employed in pharmaceutical industry.

Part I: Basic Concepts. Chapter 1: Clinical Pharmacokinetic and Pharmacodynamic Concepts. Chapter 2: Clinical Pharmacokinetic Equations and Calculations. Chapter 3: Drug Dosing in Special Populations: Renal and Hepatic Disease, Dialysis, Heart Failure, Obesity, and Drug Interactions. Part II: Antibiotics. Chapter 4: Aminoglycoside Antibiotics. Chapter 5: Vancomycin. Part III: Cardiovascular Agents. Chapter 6: Digoxin. Chapter 7: Lidocaine. Chapter 8: Procainamide and N-Acetyl Procainamide. Chapter 9: Quinidine. Part IV: Anticonvulsants. Chapter 10: Phenytoin. Chapter 11: Carbamazepine. Chapter 12: Valproic Acid. Chapter 13: Phenobarbital/Primidone. Chapter 14: Ethosuximide. Part V: Immunosuppressants. Chapter 15: Cyclosporine. Chapter 16: Tacrolimus (FK506). Part VI: Other Drugs. Chapter 17: Lithium. Chapter 18: Theophylline.