Myocardial Laser Revascularization

Charles R. Bridges, MD, ScD. Chief of Cardiothoracic Surgery, Pennsylvania Hospital. Associate Professor of Surgery, University of Pennsylvania Health System Keith A Horvath, MD, Chief, Cardiothoracic Surgery Branch, National Heart, Lung and Blood Institute, NIH Bethesda Ray Chu-Jeng Chiu, MD, PhD, FRCSC, Professor of Surgery and Chair Emeritus, McGill University, Montreal General Hospital

List of Contrbutors. Preface. 1 Scientific and Historic Precedents. (OH Frazier, Marianne Bergheim, and Kamuran A. Kadipasaoglu). 2 Laser-tissue Interaction. (E. Duco Jansen and Peter Whittaker). 3 The biology of Laser-Tissue Interactions: in Vivo Comparisons and Consequences. (Peter Whittaker and E. Duco Jansen). 4 Histopathologic Effects of Transmyocardial Laser Revascularization on Myocardium: Assessment of Channel Patency. (Kamuran A. Kadipasaoglu, Egemen Tuzun, and OH Frazier). 5 Animal Models of Acute and Chronic Coronary Ischemia: Effects of TMR on Perfusion and Left Ventricular Function. (G. Chad Hughes and James E. Lowe). 6 Selection Criteria for Sole Therapy and Adjunctive Therapy in Combination with Coronary Artery Bypass Graft Surgery. (Charles R. Bridges and Kapil Gopal). 7 Results of Prospective Randomized Trials. (Keith B. Allen and Keith A Horvath). 8 Combination Therapy with Coronary Artery Bypass Grafting. (Kapil Gopal and Charles R. Bridges). 9 Operative Techniques of Transmyocardial Laser Revascularization. (Keith A. Horvath). 10 The Open Channel Hypothesis for Transmyocardial Revascularization: a Re-examination. (Peter Whittaker and Chad E. Darling). 11 Mechanisms of TMR: Angiogenesis. (Marc P Pelletier, Varun Kapila, and Ray CJ Chiu). 12 Myocardial Sinusoids and Non-compaction: Embryology and Relevance to the Adult Coronary Circulation. (Ray C.J. Chiu, Stephen J. Korkola, and Kevin Lachapelle). 13 Remodeling of the Intrinsic Cardiac Nervous System Following Chronic Transmyocardial Laser Therapy. (J. Andrew Armour). Index