Principles of Clinical Gastroenterology

Tadataka Yamada, MD is President of the Bill & Melinda Gates Foundation Global Health Program, where he leads the foundation's efforts to apply technological solutions to the healthcare problems of the developing world. Dr. Yamada was chairman of R&D at GlaxoSmithKline from 2001-2006, and joined the company's Board in 2004. Previously, he was Chairman of the Department of Internal Medicine at the University of Michigan Medical School and Physician-in-Chief of the University of Michigan Medical Center. He is past President of the Association of American Physicians, past President of the American Gastroenterological Association, Master of the American College of Physicians and a member of the Institute of Medicine of the National Academy of Sciences. David H. Alpers, MD, William B. Kountz Professor of Medicine, Department of Internal Medicine, Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri, USA Anthony N. Kalloo, MD, Associate Professor of Medicine, Johns Hopkins University School of Medicine; Director, Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, USA Neil Kaplowitz, MD, Thomas H. Brem Chair, Professor of Medicine, Chief, Division of Gastrointestinal and Liver Diseases; Director, University of Southern California Liver Disease Research Center, Los Angeles, California, USA Chung Owyang, MD, Professor of Internal Medicine, H. Marvin Pollard Collegiate Professor and Chief, Division of Gastroenterology, University of Michigan Health System, Ann Arbor, Michigan, USA Don W. Powell, MD, Professor, Internal Medicine, Professor, Neuroscience and Cell Biology; Director, Division of Gastroenterology and Hepatology Program Director, General Clinical Research Center, The University of Texas Medical Branch, Galveston, Texas, USA

Contributors. Preface. 1 Clinical decision making: Philip S. Schoenfeld (University of Michigan). 2 Economic analysis in the diagnosis and treatment of gastrointestinal diseases: John M. Inadomi (University of California). 3 Psychosocial factors in the care of patients with functional gastrointestinal disorders: Bruce D. Naliboff (University of California), Jeffrey M. Lackner (The State University of New York), Emeran A. Mayer (University of California). 4 Approach to the patient with dyspepsia and related functional gastrointestinal complaints: Nicholas J. Talley (Mayo Clinic Jacksonville), Gerald Holtmann (University of Adelaide, Australia). 5 Approach to the patient with dysphagia, odynophagia, or noncardiac chest pain: Chandra Prakash Gyawali (Washington University School of Medicine), Ray E. Clouse (Washington University School of Medicine). 6 Approach to the patient with gastroesophageal reflux disease: Joel E. Richter (Temple University). 7 Approach to the patient with dyspepsia and peptic ulcer disease: Andrew H. Soll (University of California), David Y. Graham (Baylor College of Medicine). 8 Approach to the patient with gross gastrointestinal bleeding: Grace H. Elta (University of Michigan Health System), Mimi Takami (University of Michigan). 9 Approach to the patient with occult gastrointestinal bleeding: David A. Ahlquist (Mayo Clinic College of Medicine), Graeme P. Young (Flinders University of South Australia). 10 Approach to screening for colorectal cancer: Graeme P. Young (Flinders University of South Australia), James E. Allison (University of California). 11 Approach to the patient with unintentional weight loss: Andrew W. DuPont (The University of Texas Medical Branch). 12 Approach to the patient with obesity: Louis A. Chaptini (University of Medicine and Dentistry of New Jersey), Steven R. Peikin (University of Medicine and Dentistry of New Jersey). 13 Approach to the patient with nausea and vomiting: William L. Hasler (University of Michigan). 14 Approach to the patient with abdominal pain: Pankaj Jay Pasricha (Stanford University). 15 Approach to the patient with gas and bloating: William L. Hasler (University of Michigan Health System). 16 Approach to the patient with acute abdomen: Rebecca M. Minter (University of Michigan Health System), Michael W. Mulholland (University of Michigan). 17 Approach to the patient with ileus and obstruction: Klaus Bielefeldt (University of Pittsburgh), Anthony J. Bauer (University of Pittsburgh). 18 Approach to the patient with diarrhea: Don W. Powell (University of Texas Medical Branch). 19 Approach to the patient with suspected acute infectious diarrhea: John D. Long (Wake Forest University), Ralph A. Giannella (University of Cincinnati). 20 Approach to the patient with constipation: Satish S.C. Rao (University of Iowa). 21 Approach to the patient with abnormal liver chemistries: Richard H. Moseley (University of Michigan). 22 Approach to the patient with jaundice: Raphael B. Merriman (University of California), Marion G. Peters (University of California). 23 Approach to the patient with ascites and its complications: Guadalupe Garcia-Tsao (Yale School of Medicine). 24 Approach to the patient with central nervous system and pulmonary complications of end-stage liver disease: Javier Vaquero (University of Montreal), Andres T. Blei (Northwestern University, Chicago), Roger F. Butterworth (University of Montreal). 25 Approach to the patient with acute liver failure: Ryan M. Taylor (University of Michigan), Robert J. Fontana (University of Michigan). 26 Approach to the patient with chronic viral hepatitis B or C: Sammy Saab (University of California), Hugo Rosen (University of Colorado). 27 Approach to the patient with a liver mass: John A. Donovan (University of Southern California), Edward G. Grant (University of Southern California). 28 Approach to gastrointestinal and liver diseases in pregnancy: Willemijntje A. Hoogerwerf (University of Michigan). 29 General nutritional principles: David H. Alpers (Washington University School of Medicine), Beth Taylor (Barnes-Jewish Hospital, Missouri), Samuel Klein (Washington University School of Medicine). 30 Approach to the patient requiring nutritional supplementation: David H. Alpers (Washington University School of Medicine), Beth Taylor (Barnes-Jewish Hospital, Missouri), Samuel Klein (Washington University School of Medicine). 31 Genetic counseling for gastrointestinal patients: Cindy Solomon (Myriad Genetic Laboratories, Utah), Deborah W. Neklason (University of Utah), Angela Schwab (Intermountain Healthcare, Utah), Randall W. Burt (University of Utah). Index