Cytokines and the Brain

I. History
The history of Neuroimmune Biology:

II. Cytokines and in the brain;
A.Cytokines, their receptors and signal transduction in the brain;
Cytokine Receptors in the Brain;
Interleukin-1 and Corticotropin Releasing Factor Receptors in the Hypothalamic-Pituitary-Adrenal Axis;
Brain interleukin-1â expression and action in the absence of neuropathology;
Interleukin 1â signal transduction via the sphingomyelin pathway in brain cells;
Blood-brain barrier transport of cytokines;

B. Cytokines in brain physiology
Cytokines in synaptic function;
Interleukin-2 as a Neuroregulatory Cytokine;
Cytokines and Extracellular Matrix Remodeling in the Central Nervous System;
Acidic fibroblast growth factor, a satiety substance, variegated physiological significance;
Cytokines and Sleep;

C. Chemokines in the brain;
Chemokines, their receptors and significance in brain function;

IV. Immune response in the brain;
Immune and inflammatory responses in the CNS: modulation by astrocytes;
Immune Response in the Brain: Glial Response and Cytokine Production;

V. Cytokines in pathophysiological brain responses;
A. Brain-immune interaction
Lymphocytes and adrenergic sympathetic nerve system: the role of cytokines;
Cytokines in Neural Signaling to the Brain;
Interleukin-2 gene expression in CNS cells after stress and antigen application;
Sex hormones and cytokines in CNS pathology and repair;
Involvement of brain cytokines in stress-induced immunosuppression;
Neuroprotective Effects of Inflammation in the Nerves System;

VI. Disease;
Brain Response to Endotoxin;
Cytokines in Demyelinating Disease;
The Cytokines and Depression Hypothesis: An Evaluation;
Clinical Relevance: Cytokines in Alzheimer’s Disease;

VII. Cytokines and behaviour;
Cytokines and immune-related behaviors;
The production and effects of cytokines depend on brain lateralization;