Research on the Neurobiology of Alcohol Use Disorders

Leo Sher, MD is a psychiatrist with a background in internal medicine. His areas of research and clinical expertise include neurobiology, diagnosis, and treatment of mood, anxiety, and personality disorders, alcoholism, and suicidal behavior. He is Associate Professor of Psychiatry at Icahn School of Medicine at Mount Sinai and Director of the Inpatient Psychiatry Service at the James J Peters VA Medical Center in New York. He has authored about 600 scientific publications, is a reviewer for numerous medical journals, the recipient of several awards and the first researcher in North America who introduced the use of the combined dexamethasone suppression/corticotropin-releasing hormone stimulation test for psychiatric purposes. Dr. Sher has experience as a forensic psychiatric expert and consultant.

Preface; Neurobiology of Alcohol Use Disorders: Plenty of Room for New Research; Epidemiology of Alcohol Use, Abuse, and Dependence; Recognising Alcohol Use Disorders; Biochemical Measures of Alcohol Consumption; Neurobiological Correlates of the Disposition and Maintenance of Alcoholism; Is Thiamine Deficiency One Cause of Familial Alcoholism?; Pharmacogenomics and the Future of Alcohol Dependence Treatment; Acamprosate: Elucidating the Mechanism of Action and Its Protective Effects; Neurobiology of Suicidal Behaviour in Alcohol Use Disorders; Effect of Natural and Synthetic Polyamines on Ethanol Intake; Glial and Neuronal Packing Density in the Orbitofrontal Cortex in Alcohol Dependence; Ethanol Exposure and Pro-enkephalin mRNA Expression in Regions of the Mesocorticolimbic System; Importance of Alcohol Induced Modulation of Nitric-oxide Synthase in the Brain; Neural Stem Cells: A potential Mechanism in Alcoholic Neurodegeneration and Recovery; Alcohol-induced Blood-brain Barrier Dysfunction; Hypothalamic-pituitary-adrenocortical Axis Activity and Alcohol Use Disorders, Falk Kiefer and Christoph von der Goltz; Cognitive Deficits in Individuals Prenatally Exposed to Alcohol; Genetic Influences on Alcohol Use and Dependence; Index