Ciba Foundation Symposium 152 – The Biology of Nicotine Dependence -  Ciba Foundation

Ciba Foundation Symposium 152 – The Biology of Nicotine Dependence

Software / Digital Media
274 Seiten
2007
John Wiley & Sons Inc (Hersteller)
978-0-470-51396-5 (ISBN)
126,38 inkl. MwSt
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Nicotine is considered to be the main agent in the maintenance of the tobacco smoking habit and is largely responsible for the behavioral and physiological responses to the inhalation of tobacco smoke. This work presents advances made in the elucidation of the action of nicotine in the body--essential information for developing treatments to help people give up smoking. The book reviews the progress made in identifying nicotinic acetylcholine receptors in the brain, using the techniques of molecular biology to characterize receptors and investigate the functional differences between receptors composed of different types of subunits. Sex-specific differences in the response to nicotine, the effects of nicotine on locomotor activity, and its still-debated influence on cognitive performance are considered. The book also examines the habit-forming role of nicotine, the development of tolerance to nicotine, and the less clearly understood phenomenon of withdrawal. Also discusses some potential therapeutic strategies.

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.

Partial table of contents: Behavioral Pharmacology of Nicotine: Implications for Multiple Brain Nicotinic Receptors (I. Stolerman). Mechanism of Action of the Nicotinic Acetylcholine Receptor (J. Steinbach). Modulation of Nicotine Receptors by Chronic Exposure to Nicotinic Agonists and Antagonists (A. Collins, et al.). Regulation of Endocrine Function by the Nicotinic Cholinergic Receptor (K. Fuxe, et al.). Effects of Nicotine on Cerebral Metabolism (E. London). Mesolimbic Dopamine Activation--The Key to Nicotine Reinforcement? (P. Clarke). Effect of Nicotine on Dynamic Function of Brain Catecholamine Neurons (T. Svensson, et al.). Pharmacokinetic Considerations in Understanding Nicotine Dependence (N. Benowitz). Behavioral Studies in Humans: Anxiety, Stress and Smoking (O. Pomerleau & C. Pomerleau). Index of Contributors. Subject Index.

Erscheint lt. Verlag 28.9.2007
Verlagsort New York
Sprache englisch
Maße 136 x 256 mm
Gewicht 560 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete
ISBN-10 0-470-51396-9 / 0470513969
ISBN-13 978-0-470-51396-5 / 9780470513965
Zustand Neuware
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