Ciba Foundation Symposium 131 – Tumour Necrosis Factor and Related Cytotoxins

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.

Natural Production and Release of Tumour Necrosis Factor (G. Gifford, D. Flick). Possible Relationships between in vivo Antitumour Activity and Toxicity of Tumour Necrosis Factor-a (M. Palladino et al.). Human Tumour Necrosis Factors: Structure and Receptor Interactions (B. Aggarwal et al.). Cytocidal Activity of Tumour Necrosis Factor: Protection by Protease Inhibitors (C. Baglioni et al.). Lymphotoxin: Cloning, Regulation, and Mechanism of Killing (N. Ruddle et al.). Physiological Responses to Cachectin (K. Tracey et al.). Structure-function Relationship of Tumour Necrosis Factor and Its Mechanism of Action (W. Fiers et al.). Relationship of Tumour Necrosis Factor and Endotoxin to Macrophage Cytotoxicity, Haemorrhagic Necrosis and Lethal shock (J. Rothstein, H. Schreiber). Antitumour Effects of Necrosis Factor: Cytotoxic or Necrotizing Activity and Its Mechanism (K. Haranaka et al.). Effects of Tumour Necrosis Factor on Human Tumour Xenografts in Nude Mice (F. Balkwill et al.). Effects of Tumour Necrosis Factor and Related Cytokines on Vascular Endothelial Cells (J. Pober). Antiparasitic Effects of Tumour Necrosis Factor in vivo and in vitro (J. Playfair, J. Taverne). Clinical Studies with Tumour Necrosis Factor (D. Spriggs et al.). Summary (L. Old). Index of Contributors. Subject Index.