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Humoral Immunity in Neurological Diseases

D. Karcher (Herausgeber)

Buch | Hardcover
683 Seiten
1979
Kluwer Academic/Plenum Publishers (Verlag)
978-0-306-40195-4 (ISBN)
85,55 inkl. MwSt
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I Spontmeous and Experimental Diseases.- A. Multiple Sclerosis.- Cellular Immunology in Multiple Sclerosis: a) Introduction and History.- Cellular Immunology in Multiple Sclerosis: b) Response to Several Viruses.- Cellular Immunology in Multiple Sclerosis: c) Studies on Immune Regulatory Cells.- Humoral Immunity in Disease with Special Reference to Multiple Sclerosis.- Cellular Immune Function to Measles Antigen in Normal Subjects and Multiple Sclerosis-Skin Testing with Autologous CSF and Other Antigens in Multiple Sclerosis.- Cases of Acute Measles Infection in Multiple Sclerosis Patients.- Pathogenetic Considerations in Multiple Sclerosis: Is MS a Chronic Variant of Postinfectious Encephalomyelitis ?.- Heterogeneous Humoral Autoimmune Response in Multiple Sclerosis.- B. Subacute Sclerosing Panencephalitis.- Subacute Sclerosing Panencephalitis.- Comparative Neuropathology of Subacute Sclerosing Panencephalitis.- Cross-Idiotypic Specificity among Immunoglobulins in Subacute Sclerosing Panencephalitis and Multiple Sclerosis.- The Virological State in Subacute Sclerosing Panencephalities.- Cellular Immunity in Subacute Sclerosing Panencephalitis.- Progressive Rubella Panencephalitis.- C. Genetic Implications.- Multiple Sclerosis and the HLA Determinants.- HLA and Multiple Sclerosis: Genetic Considerations..- Familial Aspects of Multiple Sclerosis: a Rational Prophylactic Therapy.- D. Animal Diseases.- Distribution of Scrapie Infectivity in Various Mouse Tissues at Early Times after Infection.- Immunoglobulin G Levels in the Sera of Herdmick Sheep with Natural Scrapie.- Visna in Sheep.- Old Dog Encephalitis: A Clinical and Serological Study.- Experimental Murine Autoimmune Encephalomyelitis.- II Restricted Heterogeneity (Oligoclonal Reaction).- A. Cerebrospinal Fluid Methodology.- Isoelectric Focusing and Crossed Immunoelectro-focusing of CSF Proteins-Especially Immunoglobulins.- Study of Oligoclonal CSF by new Immunofixation Techniques Following Electrophoresis on Cellulose Acetate Gel.- Radioimmunoassay of Immunoglobulins in Cerebrospinal Fluid.- Measurement of Blood/CSF Permeability Coefficients and of Intrathecal Synthesis of IgG by Capillary Isotachophoresis.- Study on the Iinmunoglobulins (IgG, IgA and IgM) in the Cerebrospinal Fluid and Serum in Cases of Suppurative Meningitis and Viral Encephalitis.- Viral Antibody and Protein Studies of Cerebrospinal Fluid: Diagnostic Usefulness in Multiple Sclerosis.- The Clinical Significance of Immunoglobulin G (IgG) Determinations in the CSF of Multiple Sclerosis Patients.- Determination of IgM in the Cerebrospinal Fluid by Particle Counting Immnoassay (PACIA).- Local and General Immunity in CNS Diseases.- Nucleic and Viral Antibodies in Serum and CSF of MS Patients.- Problems with Qualitative CSF Antibody Tests.- Immunocytological CSF Alterations and Brain Tumors.- Study of Humoral Immunity in Cerebrospinal Fluid of Patients Infected with Schistosomiasis.- B. IgG Restricted Heterogeneity.- Restricted Heterogeneity of the IgG in Neurology.- Oligoclonal Immune Responses in the Central Nervous System (CNS) in Connection with Virus Infections and CNS Diseases of Unknown Etiology.- Oligoclonal Virus Antibodies in Healthy Adults and Neurological Patients.- C. Immunochemistry.- Immunoglobulin Structure and Function: Idiotypy and the Oligoclonal Response.- Structural Studies of Immunoglobulins from Patients Affected by Subacute Sclerosing Panencephalitis.- Insights Gained from the Study of Homogeneous Rabbit Antibodies.- Circulating Immune, Complexes in Neurological Disorders.- D. Viral Antigens.- Partial Purification of Multiple Sclerosis Specific Antigens.- Characterization of Measles Specific Proteins Synthesized from Acutely and Persistently Infected Cells.- New Polypeptides in Measles Virus Infected Vero Cells.- The Fate of Antigen-Antibody Complexes on Measles Virus-Induced Giant Cells.- Induction of Infectious Virus and Viral Surface Antigen in Vero Cells Persistently Infected with Junin Virus.- E. Central Nervous System Antigens.- Antibody to Oligodendroglia.- Brain Specific Proteins in Cerebrospinal Fluid.- Loss of a Brain-Specific Antigen (Alpha2 Glycoprotein) in Human Glial Tumors.- Neuroblastoma Cytoskeleton shown by Immunofluorescence.- In Vitro Assessment of the Cell-Mediated Immune Response Towards Human Gliomas.- Macrophage-Specific Antigens.- F. Nervous System Response.- Oligoclonal IgG Bands and Measles Antibodies in Multiple Sclerosis (MS) CSF and Brain Extracts.- Characterization of the Humoral Immune Response Within the CNS by Immunofixation.- Effects of Serum Factors Upon Myelin Organization in Organotypic Cultures of Nervous Tissue.- The Enhancing Effect of Multiple Sclerosis Brain Homogenates on the Active E Rosette Forming Lymphocytes.- Further Studies on the Elution of Immunoglobulin from Multiple Sclerosis Brain.- Interactions of Vaccinia Virus with the Myelin Membrane.- Functional Impairment of Neuronal Model Cells Induced by Persistent Viral Infection.- Active T Cells in Blood and CSF in MS and Controls.- Isolation and Characterization of the T Cell Receptor for the Basic Encephalitogenic Protein in EAE.- The Influence of the T Immune System on the Appearance of Homogeneous Immunoglobulins in Man and Experimental Animals.- Regulatory Interactions Between Cells in Immune Responses.- Inhibiting Factor: General Review.- B Lymphocyte Function in SSPE: Is there Lack of Suppressor Cells ?.- Topic III Therapeutic Considerations.- Pathogenesis of Multiple Sclerosis Lesion: Implications for Therapy.- Immunologic Factors in the Suppression of Experimental Allergic Encephalomyelitis: Relevance to Multiple Sclerosis.- Four Laboratory Methods for the Diagnosis of Multiple Sclerosis: A Programme for Treatment and Possible Prophylaxis.- Suppression of Experimental Allergic Encephalomyelitis with a Synthetic Copolymer-Relevance to Multiple Sclerosis.- Intrathecal Methotrexate in Multiple Sclerosis.- Remissions and Exacerbations during Cyclophosphamide and Steroid Therapy in a Case of Neuromyelitis Optica.- Intrathecal Administration of Interferon in Multiple Sclerosis Patients ?.- Varia-Other Diseases.- Renal and Skin Biopsy Findings in Amyotrophic Lateral Sclerosis.- Some Muscular Changes in Patients with Schistosomiasis.- Immunological Deficiency in the Down Syndrome: Importance of the Age Factor.- Conclusions.- Participants.

Reihe/Serie NATO Science Series A ; 24
Zusatzinfo biography
Sprache englisch
Gewicht 1341 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Studium 2. Studienabschnitt (Klinik) Pathologie
ISBN-10 0-306-40195-9 / 0306401959
ISBN-13 978-0-306-40195-4 / 9780306401954
Zustand Neuware
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