Oxygen Transport to Tissue

Session 1 - Oxygen Electrodes and Blood Monitoring Devices.- The Bitumen PO2 Electrode - A New Method to Manufacture PO2 Needle Electrodes.- A Working Equation for Oxygen Sensing Disk Electrodes.- Variations on the Response Characteristics of Oxygen Electrodes.- Directly Heated Transcutaneous Oxygen Sensor.- A Self-Calibrating, Continuous in vivo PO2 and PCO2 Monitor.- Thin Ring PO2 Electrode Using Gold Paste and Its Application to the Study of the Effects of Venous Occlusion on Skin PO2.- How to Quantify Skeletal Muscle Capillarity.- Staining of PO2 Measuring Points Demonstrated for the Rat Brain Cortex.- Discussion.- Session 2 - Optical Methods.- First Cryophotometric Measurements of the HbO2 Saturation in the Cat Carotid Body.- Multiple Wavelength Reflectance Oximetry in Peripheral Tissues.- Myoglobin Saturation and Calculated PO2 in Single Cells of Resting Gracilis Muscles.- The Myoglobin Probed Optical Studies of Myocardial Energy Metabolism.- The Intracellular Heterogeneity of Oxygen Concentrations as Measured by Ultraviolet Television Microscopy of PBA Fluorescence Quenching by Oxygen.- Application of the Optode Measurements of Surface PO2 and PCO2 of the Isolated Guinea-Pig Heart.- A New Method for Measuring the Oxygen Content in Microliter Samples of Gases and Liquids: The Oxygen Cuvette.- Factors Influencing the Correction Factor Used to Eliminate the Apparent NADH Fluorescence Changes Caused by Alterations in Cerebrocortical Blood Content.- Organ Absorbance and Fluorescence Spectrophotometry and Its Application to Oxygen-Dependent Parameters.- An Experimental Model of the Krogh Tissue Cylinder: Two-Dimensional Quantitation of the Oxygen Gradient.- Discussion.- Session 3 - Model Systems.- Multi-Capillary Model for Oxygen Transport to Skeletal Tissue.- Dynamic Hypoxic Hypoxemia in Brain Tissue: Experimental and Theoretical Methodologies.- Mathematical Model of Respiratory Gas Exchange at Stationary Conditions.- Calculation of the Facilitation of O2 or CO Transport by Hb or Mb by Means of a New Method for Solving the Carrier-Diffusion Problem.- The Effect of Deoxygenation Rate of the Erythrocyte on Oxygen Transport to the Cardiac Muscle.- Gas Transfer Through the Skin: A Two-Layer Model Relating Transcutaneous Flux to Arterial Tension.- Electrical Potentials During Carbon Dioxide Transport in Hemoglobin Solutions.- Interpretation of Oxygen Disappearance Rates in Brain Cortex Following Total Ischaemia.- Analysis of Oxygen Transport in Bullfrogs.- Distribution of Intracapillary O2-Supply and Tissue PO2 in Canine Left Ventricle During Normoxia - An Analysis of Kryophotometrically Measured HbO2 Saturation with a Diffusion Model.- Metabolism Prediction Based on Measurement of PO2 and Flow at the Same Locus During Seizures and Barbiturate Suppression of EEG.- A Computer Analysis of Graded Ischemia in Brain.- A Comparison of Two Nonclassical Models for Oxygen Consumption in Brain and Liver Tissue.- Models for Pulsed Polarographic Electrodes.- Mathematical Simulation of Oxygen and Carbon Dioxide Transport in Fetal Brain.- Some Effects of High Altitude and Polycythaemia on Oxygen Delivery.- The Theoretical Effect of DPG Upon Oxygen Diffusion in Erythrocytes.- Discussion.- Session 4 - Cellular Respiration and O2 Transport.- On the Mechanism of Regulation of Cellular Respiration. The Dependence of Respiration on the Cytosolic [ATP], [ADP], and [Pi].- Regulation of Mitochondrial Respiration in Intact Tissues: A Mathematical Model.- In vivo Studies of Mitochondrial Respiration.- Induction by Hypoxia of a New Haemoglobin-Like Pigment.- Myoglobin-O2-Saturation Profiles in Muscle Sections of Chicken Gizzard and the Facilitated O2 Transport by Mb.- Simultaneous Measurement of Glucose and O2 Consumption in Cell Suspensions with Minielectrodes.- Density Dependent Energy Changes and Adaptive Growth in Populations of Mouse Fibroblasts in vitro.- Direct Determination of Local Oxygen Consumption of the Brain Cortex in vivo.- Study of Tissue Oxygen Gradients by Single and Multiple Indicators.- Discussion.- Session 5 - Oxygen, Radiation, and Neoplasia.- Increase in Brain Tissue Oxygen Availability Induced by Localized Microwave Hyperthermia.- A Pulse-Radiolysis Study on Active Oxygen.- Oxygen Diffusion Constants D and K of Tumor Tissue (DS-Carcinosarcoma) and Their Temperature Dependence.- Intracapillary HbO2 Saturation in Tumor Tissue of DS-Carcinosarcoma During Normoxia.- Oxygen Levels in Tumors in C3H Mice During Hyperthermia: Initial Data.- Prevention of Ionizing Radiation-Induced Liver Microcirculation Changes by the Use of Flow Improvers.- Discussion.- Session 6 - Oxygen Transport in Disease.- Oxygen Transport Impairment Induced by Three Major Cardiovascular Risk Factors.- Oxygen Pressure Values in the Ischemic Muscle Tissue of Patients with Chronic Occlusive Arterial Disease.- Computer Simulation of the Human Thoracic Aorta to Evaluate the Possible Role of Smoking in Atherogenesis.- Synchronous Tracer Injection for O2 Uptake and CO2 Production Measurement.- Measurements of Local Oxygen Pressure in Skeletal Muscle of Patients Suffering from Disturbances of Arterial Circulation.- Increased Hemoglobin-Oxygen Affinity in Patients with Pancreatitis Associated with Type I and V Hyperlipoproteinemia.- Effects of Coronary Occlusion on Myocardial Oxygen and Pulsatile Intramyocardial Pressure.- Homeostatic Responses to Increased Oxygen Affinity.- Hemoglobin-Oxygen Affinity in Organic Heart Disease.- Discussion.- Session 7 - Fetal and Maternal Oxygenation.- Microelectrode Studies in the Brain of Fetal Rats and New Born Rats.- The Effect of Acidosis on Red Cell 2,3-DPG and Oxygen Affinity of Whole Fetal Blood.- Oxygen Affinity Changes in the Red Cells of Embryonic and Neonatal Mice.- Temporal Correlations Between Plasma Ovarian Steroid Hormone Levels and Intrauterine Oxygen Tension in the Guinea Pig.- Oxygen Consumption and Oxygen Diffusion in Isolated Human Term Placental Lobules Perfused in vitro.- Hemodynamics and Oxygen Diffusion in the Cotyledon of the Human Placenta.- Respiratory Gas Transport in Blood During Pregnancy with Hemoglobin Concentrations Below 12g/100ml.- Discussion.- Session 8 - Hypoxia, Ischemia, Shock.- Relationship Between Erythropoietin Levels and Intrarenal Oxygenation During Anuric Hemorrhagic Shock.- Modifications of Somatosensory Evoked Cortical Potentials During Hypoxia in the Awake Rabbit.- Tissue-PO2 (PGO2) in the Carotid Body of the Cat and the Tidal Volume (V) during Normovolaemic Haemodilution.- Oxygen Extraction in Severely Anemic Dogs After Infusion of NaHCO3 or HCl.- The Effect of Dextrose/Insulin Infusion on the Duration of Respiratory Activity in the Anoxic Rat.- Oxygen Consumption and Oxygen Extraction of the Feline Liver Under Different Types of Induced Hypoxia.- The Effects of Low O2 Supply on the Respiratory Activity, Reduced Pyridine Nucleotide Fluorescence, K+ Efflux and the Surface PO2 and PCO2 of the Isolated, Perfused Rat Liver.- Disturbances of Extracellular pK, pNa, and pH During No-Flow Anoxia.- Cytochrome Oxidase and Urate Oxidase as Intracellular O2 Indicators in Studies of O2 Gradients During Hypoxia in Liver.- Flow Stasis, Blood Gases and Glucose Levels in the Red Pulp of the Spleen.- Intestinal O2 Consumption Under Low Flow Conditions in Anaesthetized Cats.- Tissue Blood Exchange and Tissue Oxygen Tension in Relation to Total Body Oxygen Consumption in Experimental Surgical Shock.- Skeletal Muscle PO2: Indicator of Peripheral Tissue Perfusion in Haemorrhagic Shock.- Monitoring of Tissue PO2 in Patients During Intensive Care.- Enhancement of CO2-Elimination by Intrapulmonary High Frequency Pressure Alternating During "Apnoeic Oxygenation".- Changes in Cerebrocortical PO2 -Distribution, rCBF and EEG During Hypovolemic Shock.- Extracellular K+ and H+ Activities in the Brain Cortex During and After a Short Period of Ischaemia and Arterial Hypoxia.- Regional Hemodynamic and Metabolic Alterations in Focal Cerebral Ischemia: Studies of Diaschisis.- Oxygen and Carbon Dioxide Tensions in the Gastrocnemius Muscles of Patients with Lower Limb Arterial Ischaemia.- Effects of Ischemia on the Oxygen Diffusion Coefficients in the Brain Cortex.- Oxygen Supply to the Cirrhotic Liver Following Various Portacaval Shunt Procedures.- PO2 Histograms and Extracellular Activity of K+ of Skeletal Muscle in Tourniquet Shock.- Effect of Ouabain on Cortical Potassium Activity During Anoxic Depolarization.- The Size of the Hypoxic Zone at the Border of an Anoxic Region Within the Tissue.- Discussion.- Session 9 - Tissue PO2 and Cell Function.- The Effect of Chronic Hypoxia on Wound Healing.- Oxygen and Epidermal Wound Healing.- Oxygen Pressure and Ictal Activity in the Cerebral Cortex of Artifically Ventilated Rats During Exposure to Oxygen High Pressure.- Simultaneous Measurement of PO2 and Flow at the Same Locus During Seizures and Barbiturate Suppression of EEG.- The Sensitivity of Aplysia Giant Neurons to Changes in Extracellular and Intracellular PO2.- Oxygen Diffusion, Conductivity and Solubility Coefficients in the Microarea of the Brain.- Transient Metabolic and Vascular Volume Changes Following Rapid Blood Pressure Alterations Which Precede the Autoregulatory Vasodilation of Cerebrocortical Vessels.- The Influence of Electrical Stimulation on Cortex PO2 Level in the Rat Brain.- Local Tissue PO2 in Kidney Surgery and Transplantation.- Measurements of Oxygen Partial Pressure and Single-Unit Action Potentials in the Parieto-Visceral Ganglion of Aplysia californica.- The Responses of an Awake Brain to HPO Under Increased CO2 Concentrations.- Oxygen Transport to the Inner Ear.- Kinetics of Changes in PO2 and Extracellular Potassium Activity in Stimulated Rat Sympathetic Ganglia.- Evidence for Existence of Intramyocardial Steal.- The Interrelation Between CBF, Energy Metabolism and ECoG in a New Awake Brain Model.- Tissue PO2 Changes in Acute Inflammation.- Thresholds of Ischaemia in Brain Cortex.- Discussion.