A Textbook of In Vitro Fertilization and Assisted Reproduction

An introduction to Bourn Hall. Investigation of the infertile couple for assisted conception. The investigation and therapeutic options for infertile men presenting in assisted conception units. Laboratory investigation of the infertile male. The use of GnRH agonists and antagonists in infertility. Superovulation strategies in assisted conception. Superovulation for assisted conception: the new gonadotropins. Polycystic ovaries and their relevance to assisted conception. Classification, pathophysiology and management of ovarian hyperstimulation syndrome. Ultrasound in assisted conception. Oocyte recovery and embryo transfer techniques for in vitro fertilization. Laboratory techniques: sperm preparation for assisted conception. Laboratory techniques: semen assessment and preparation. Embryo cryopreservation. Assisted reproduction techniques for male factor infertility: current status of intracytoplasmic sperm injection. Transport and satellite assisted reproductive technology. Alternative assisted conception techniques. Intrauterine insemination. Local regulators of embryo-endometrial interactions at implantation. Immunological aspects of embryo implantation. Optimizing implantation: diagnostic and therapeutic considerations. Current scientific developments in assisted conception. Cryopreservation of human oocytes and ovarian tissue. The outcome of assisted reproductive technology. Ectopic pregnancy following assisted reproductive technology. Oocyte donation. Embryo donation. Surrogacy. Medical informatics in assisted reproduction. The role of meta-analysis in clinical decision-making to optimize outcome. Nursing care in an assisted conception unit. The distress of infertility: impressions from 15 years of infertility counseling. Ethical aspects of assisted conception and the law. Regulation of assisted reproductive technology: The UK experience. The Australian experience. The French experience. The German experience. The Nordic experience. The USA experience. Appendix I: References and publications from Bourn Hall Clinic. Appendix II: Procedures, protocols and information sheets from Bourn Hall. Index.