Sepsis and Organ Dysfunction

Basic Pathophysiology Mechanics.- Inflammation: How Much Is Too Much and Can It Be Controlled.- Injury, Inflammation, Sepsis — Is There a Natural, Organized and Sequential Progression of Neuroendocrine, Metabolic and Cytokine Mediator Events Leading to Organ System Failure.- Genetic Predisposition to Sepsis and Organ Failure.- Regulation of the Lung Inflammatory Response.- Clinical Interventions in the Field of Sepsis What is Wrong and What is Right.- Shall We Continue to Talk About (or Use) SIRS in the Twenty-first Century.- Prevention and Treatment of Sepsis — Present and Future Problems.- Sepsis and MODS — What Is Wrong and What Is Right.- What Is Clinical Relevance? — Well Controlled Experiments in Normal Animals as Compared to Clinical Studies in Diverse Sick Patients.- The Markers of Sepsis.- Apoptosis (Programmed Cell Death) and the Resolution of Acute Inflammation.- “Untimely Apoptosis” Is the Password.- Multiple Therapeutic Agents — Will Individual Therapies, Each of Which Improves Patients, When Given Together, Change Mortality.- Endotoxaemia in Critical Illness: Rapid Detection and Clinical Relevance.- New and Old Markers in Sepsis.- From Cytokines through Immune Effector Cells to the Body.- Intravenous Immunoglobulins: Are They Helpful.- Clinical Aspects of Splanchnic Ischaemia and Oxygen Metabolism.- Is Splanchnic Perfusion a Critical Problem in Sepsis.- Metabolism and O2 Consumption in Trauma and Sepsis.- Intragastric pH (ipH) and PaCO2 Monitoring in Sepsis.