The Role of Cell Types in Hepatocarcinogenesis - Alphonse E. Sirica

The Role of Cell Types in Hepatocarcinogenesis

Buch | Hardcover
368 Seiten
1992
Crc Press Inc (Verlag)
978-0-8493-4746-7 (ISBN)
239,95 inkl. MwSt
  • Titel ist leider vergriffen;
    keine Neuauflage
  • Artikel merken
Provides a review and analysis of cell precursor relationships believed to be important in the development of hepatocellular carcinoma and other types of nonmesenchymal liver tumours. The book focuses on cell lineages in liver development and neoplastic formation in animal models and humans.
The Role of Cell Types in Hepatocarcinogenesis provides the first comprehensive, review and analysis of cell precursor relationships believed to be important in the development of hepatocellular carcinoma and other types of nonmesenchymal liver tumors. The book focuses on cell lineages in liver development and neoplastic formation in both experimental animal models and humans. It also critically reviews current information supporting the existence of a "facultative liver stem cell" and its potential role as an alternative cell of origin in the genesis of various hepatic neoplasms, including hepatocellular carcinoma.

Other significant topics covered include cellular and viral oncogenes, p53 gene and growth factors in hepatocarcinogenesis, and the use of newly developed transgenic animal and cell culture models designed for investigating the pathogenesis of hepatocellular carcinoma. Numerous figures and tables illustrate difficult concepts, and an extensive listing of references is included. The Role of Cell Types in Hepatocarcinogenesis is a practical reference volume that basic and clinical researchers in liver carcinogenesis, development, and differentiation will find useful in their day-to-day work.

On Cells of Origin of Liver Cell Cancer (E. Farber). Clonal Analysis of Hepatic Neoplasms by Mosaic Pattern (W.C. Weinberg, Y.K. Ng, and P.M. Iannaccone). Histogenesis and Pathobiology of Mouse Hepatocellular Neoplasms (S. Goldfarb and T.D. Pugh). Origin and Pathology of Hepatoblastomas in Mice (B.A. Diwan, J.M. Ward, and J.M. Rice). Oval Cells in Liver Carcinogenesis: Cell Lineages in Hepatic Development and the Identification of Facultative Stem Cells in Normal Liver (N. Fausto, J.M. Lemire, and N. Shiojiri). Growth and Differentiation of Stem Cells in Adult Rat Liver (S.S. Thorgeirsson and R.P. Evarts). The Role of Bipotential Progenitor Cells in Liver Ontogenesis and Neoplasia (N. Marceau, M.-J. Blouin, M. Noël, N. Török, and A. Loranger). Antigenic Clues to Liver Development, Renewal, and Carcinogenesis: An Integrated Model (D.C. Hixson, R. A. Faris, L.Yang, and P. Novikoff). Differentiation Potential of Hyperplastic Bile Ductular Epithelial Cells In Rat Models of Hepatic Injury and Cholangiocarcinogenesis (A.E. Sirica, L.W. Elmore, T.W. Williams, and S.L. Cole). Cell Lineages in Human Liver Development, Regeneration, and Transformation (M.A. Gerber and S.N. Thung). Development of Intrahepatic Bile Ducts, Ductular Metaplasia of Hepatocytes and Cytokeratin Patterns in Various Types of Human Hepatic Neoplasms (P. Van Eyken and V.J. Desmet). Role of Viral and Cellular Oncogenes and Growth Factors in Hepatocarcinogenesis in Culture and In Vivo (H.C. Isom and S.C. Strom). Transgenic Mouse Models of Hepatocarcinogenesis (S. Sell and B. Knoll). Hepatocarcinogenesis in Experimental Woodchuck Hepatitis Virus Infection (B.C. Tennant).

Erscheint lt. Verlag 11.9.1992
Zusatzinfo 17 Tables, black and white
Verlagsort Bosa Roca
Sprache englisch
Maße 156 x 235 mm
Gewicht 862 g
Einbandart gebunden
Themenwelt Medizinische Fachgebiete Innere Medizin Hepatologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium Querschnittsbereiche Infektiologie / Immunologie
ISBN-10 0-8493-4746-7 / 0849347467
ISBN-13 978-0-8493-4746-7 / 9780849347467
Zustand Neuware
Haben Sie eine Frage zum Produkt?
Mehr entdecken
aus dem Bereich
Diagnostik, Differenzialdiagnostik, Therapieansätze

von Frank Fischbach; Katharina Fischbach

Buch (2016)
Thieme (Verlag)
101,00
Biology and Pathobiology

von Irwin M. Arias; Harvey J. Alter; James L. Boyer …

Buch | Hardcover (2020)
Wiley-Blackwell (Verlag)
331,65