The Role of Cell Types in Hepatocarcinogenesis
Crc Press Inc (Verlag)
978-0-8493-4746-7 (ISBN)
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The Role of Cell Types in Hepatocarcinogenesis provides the first comprehensive, review and analysis of cell precursor relationships believed to be important in the development of hepatocellular carcinoma and other types of nonmesenchymal liver tumors. The book focuses on cell lineages in liver development and neoplastic formation in both experimental animal models and humans. It also critically reviews current information supporting the existence of a "facultative liver stem cell" and its potential role as an alternative cell of origin in the genesis of various hepatic neoplasms, including hepatocellular carcinoma.
Other significant topics covered include cellular and viral oncogenes, p53 gene and growth factors in hepatocarcinogenesis, and the use of newly developed transgenic animal and cell culture models designed for investigating the pathogenesis of hepatocellular carcinoma. Numerous figures and tables illustrate difficult concepts, and an extensive listing of references is included. The Role of Cell Types in Hepatocarcinogenesis is a practical reference volume that basic and clinical researchers in liver carcinogenesis, development, and differentiation will find useful in their day-to-day work.
On Cells of Origin of Liver Cell Cancer (E. Farber). Clonal Analysis of Hepatic Neoplasms by Mosaic Pattern (W.C. Weinberg, Y.K. Ng, and P.M. Iannaccone). Histogenesis and Pathobiology of Mouse Hepatocellular Neoplasms (S. Goldfarb and T.D. Pugh). Origin and Pathology of Hepatoblastomas in Mice (B.A. Diwan, J.M. Ward, and J.M. Rice). Oval Cells in Liver Carcinogenesis: Cell Lineages in Hepatic Development and the Identification of Facultative Stem Cells in Normal Liver (N. Fausto, J.M. Lemire, and N. Shiojiri). Growth and Differentiation of Stem Cells in Adult Rat Liver (S.S. Thorgeirsson and R.P. Evarts). The Role of Bipotential Progenitor Cells in Liver Ontogenesis and Neoplasia (N. Marceau, M.-J. Blouin, M. Noël, N. Török, and A. Loranger). Antigenic Clues to Liver Development, Renewal, and Carcinogenesis: An Integrated Model (D.C. Hixson, R. A. Faris, L.Yang, and P. Novikoff). Differentiation Potential of Hyperplastic Bile Ductular Epithelial Cells In Rat Models of Hepatic Injury and Cholangiocarcinogenesis (A.E. Sirica, L.W. Elmore, T.W. Williams, and S.L. Cole). Cell Lineages in Human Liver Development, Regeneration, and Transformation (M.A. Gerber and S.N. Thung). Development of Intrahepatic Bile Ducts, Ductular Metaplasia of Hepatocytes and Cytokeratin Patterns in Various Types of Human Hepatic Neoplasms (P. Van Eyken and V.J. Desmet). Role of Viral and Cellular Oncogenes and Growth Factors in Hepatocarcinogenesis in Culture and In Vivo (H.C. Isom and S.C. Strom). Transgenic Mouse Models of Hepatocarcinogenesis (S. Sell and B. Knoll). Hepatocarcinogenesis in Experimental Woodchuck Hepatitis Virus Infection (B.C. Tennant).
Erscheint lt. Verlag | 11.9.1992 |
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Zusatzinfo | 17 Tables, black and white |
Verlagsort | Bosa Roca |
Sprache | englisch |
Maße | 156 x 235 mm |
Gewicht | 862 g |
Einbandart | gebunden |
Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Hepatologie |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
ISBN-10 | 0-8493-4746-7 / 0849347467 |
ISBN-13 | 978-0-8493-4746-7 / 9780849347467 |
Zustand | Neuware |
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